Nurofen (Ibuprofen)

Ibuprofen blocks the cyclo‑oxygenase enzymes COX‑1 and COX‑2, preventing the conversion of arachidonic acid into prostaglandins. By lowering prostaglandin levels, it reduces inflammation, diminishes pain signalling at peripheral nerve endings, and resets the hypothalamic temperature set‑point, thereby providing analgesic, antipyretic, and anti‑inflammatory effects.

The appropriate dose of Nurofen is determined by the prescribing healthcare professional based on the patient’s age, weight, clinical condition, and local regulatory guidelines. Patients should follow the prescriber’s instructions and the product label; dosing should not be altered without medical advice.

Ibuprofen is generally avoided during the third trimester of pregnancy because it may affect fetal cardiovascular function. Use in earlier trimesters should be under medical supervision. While small amounts pass into breast milk, it is usually considered compatible with breastfeeding if the prescriber deems it necessary, but alternatives are often preferred.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Nurofen (ibuprofen) offers a balanced profile of analgesic, antipyretic and anti‑inflammatory activity with a relatively short half‑life, allowing flexible dosing. Compared with aspirin, ibuprofen has a lower risk of gastrointestinal bleeding at standard doses, while it provides stronger anti‑inflammatory effects than acetaminophen, which lacks anti‑inflammatory activity.

Nurofen tablets should be stored at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use if the packaging is damaged or the tablets appear discoloured.

Nurofen is supplied as oral tablets that are swallowed whole with a full glass of water. It is intended for systemic use, and the tablets should not be crushed or chewed unless specifically advised by a healthcare professional.

Serious risks include gastrointestinal ulceration or bleeding, especially with high‑dose or prolonged use; acute kidney injury in susceptible individuals; elevated blood pressure and cardiovascular events such as myocardial infarction or stroke; and severe allergic reactions like anaphylaxis or Stevens‑Johnson syndrome.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulceration or bleeding, severe renal or hepatic impairment, uncontrolled hypertension, and patients in the third trimester of pregnancy should avoid Nurofen unless directed by a qualified healthcare professional.