Product image of Nurofen (Ibuprofen) supplied by GNH India

Nurofen

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral dosage form for oral use. It provides temporary relief of pain, reduces fever, and helps manage inflammation in adults and children when appropriate.

GNH India supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser (Poland) S.A.

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Indications & Clinical Uses

Ibuprofen works by reducing inflammation and pain pathways, making it useful for several common conditions.

  • Pain: provides temporary relief of mild to moderate pain such as headache, toothache, menstrual cramps, and musculoskeletal aches.
  • Fever: lowers elevated body temperature associated with infections or inflammatory processes.
  • Inflammation: helps control swelling and stiffness in conditions like minor sprains, strains, and arthritis flare‑ups.

How It Works

  • Ibuprofen non‑selectively inhibits cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis leads to diminished inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Stomach upset or dyspepsia
  • Nausea or mild vomiting
  • Headache
  • Dizziness
  • Mild skin rash

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe allergic reaction (anaphylaxis)
  • Kidney injury or reduced renal function
  • Elevated liver enzymes or hepatitis
  • Cardiovascular events such as heart attack or stroke

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Medical History Review: assess for existing ulcers, kidney disease, or cardiovascular risk.
  • Take With Food: ingest with meals or milk to lessen gastric irritation.
  • Avoid Concomitant NSAIDs: do not combine with other non‑steroidal anti‑inflammatory drugs.
  • Monitor Renal Function: especially in patients with dehydration or chronic kidney disease.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness helps prevent complications.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs: additive gastrointestinal toxicity.
  • Corticosteroids: heightened risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • Diuretics: may reduce renal clearance of ibuprofen.
  • Methotrexate: potential for increased toxicity at high doses.

Frequently Asked Questions

Nurofen contains ibuprofen, which is used to temporarily relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as headaches, dental pain, menstrual cramps, musculoskeletal aches, and minor injuries.

Ibuprofen blocks the activity of COX‑1 and COX‑2 enzymes, which are needed to produce prostaglandins. By lowering prostaglandin levels, it reduces the signals that cause pain, fever, and inflammation at the affected site.

The appropriate dose of Nurofen is determined by a prescriber or according to the product label. Dosage depends on the patient’s age, weight, and the specific condition being treated, and should never exceed the recommended maximum.

Ibuprofen is generally avoided in the third trimester of pregnancy because it may affect fetal circulation. During early pregnancy and while breastfeeding, use only if clearly needed and after consulting a healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nurofen (ibuprofen) offers a balance of analgesic, antipyretic and anti‑inflammatory effects similar to other NSAIDs like naproxen or diclofenac. Choice among them often depends on dosing frequency, individual tolerance, and specific safety considerations such as gastrointestinal or cardiovascular risk.

Store Nurofen at ambient temperature, preferably below 25 °C. Keep the tablets in the original container, protect them from moisture, heat and direct sunlight to maintain product stability.

Nurofen is taken orally with a full glass of water. It can be swallowed with or without food, although taking it with meals may reduce stomach irritation. Follow the dosing instructions provided by the prescriber or on the label.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, kidney injury, and increased cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use.

People with a known allergy to ibuprofen or other NSAIDs, active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or those taking anticoagulants without medical supervision should avoid Nurofen unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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