Nurofen (Ibuprofen)

Ibuprofen works by reversibly inhibiting the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins. Lower prostaglandin levels diminish pain signaling, reduce fever, and limit the inflammatory response in affected tissues.

The appropriate dose of Nurofen is determined by a prescriber or pharmacist based on the patient’s age, weight, and clinical condition. The healthcare professional will provide specific dosing instructions that should be followed exactly as advised.

Ibuprofen is generally avoided in the third trimester of pregnancy because of potential fetal risks. During the first and second trimesters, it should only be used if clearly needed and prescribed. While limited data exist for breastfeeding, short‑term use is usually considered compatible, but a healthcare provider should be consulted.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request verification of trade or institutional credentials. The sales team then replies with pricing, availability, shipping details and any necessary import documentation.

Both ibuprofen (Nurofen) and acetaminophen relieve pain and reduce fever, but ibuprofen also has anti‑inflammatory properties. Ibuprofen works by inhibiting COX enzymes, while acetaminophen’s exact mechanism is less clear and does not significantly affect inflammation. Ibuprofen may cause gastrointestinal side effects, whereas acetaminophen carries a risk of liver toxicity at high doses.

Nurofen tablets should be stored at ambient temperature, preferably below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use it after the expiry date printed on the packaging.

Nurofen is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food or milk may reduce stomach irritation. Swallow the tablet whole; do not crush or chew unless the product label specifically permits it.

Serious risks include gastrointestinal bleeding or ulcer perforation, especially with prolonged use or in patients with a history of ulcers. Kidney injury can occur, particularly in dehydrated individuals or those with pre‑existing renal disease. Severe allergic reactions such as anaphylaxis, though rare, require immediate medical attention.

People with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, or significant kidney impairment should avoid Nurofen. It is also contraindicated in the third trimester of pregnancy and should be used with caution in patients taking anticoagulants or certain antidepressants.