Product image of Nurofen (Ibuprofen) supplied by GNH India

Nurofen

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet for oral use. It is used to relieve mild to moderate pain, reduce fever, and treat inflammation in adults and children when appropriate.

GNH India supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare B.V.

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Indications & Clinical Uses

Ibuprofen acts systemically to alleviate pain and inflammation across several common conditions.

  • Headache: reduces pain intensity and associated discomfort.
  • Dental pain: provides relief after dental procedures or toothache.
  • Musculoskeletal pain: eases aches from sprains, strains, and back pain.
  • Fever: lowers elevated body temperature in febrile states.
  • Arthritis: diminishes joint inflammation and stiffness in osteoarthritis and rheumatoid arthritis.

How It Works

  • Ibuprofen inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, decreasing the synthesis of prostaglandins that mediate pain, fever, and inflammation. By reducing prostaglandin levels, it diminishes peripheral sensitization of nociceptors and lowers the hypothalamic set‑point for body temperature, resulting in analgesic, antipyretic, and anti‑inflammatory effects.

Side Effects

Adverse reactions may occur with ibuprofen use.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia, or mild abdominal discomfort.
  • Headache: transient headache unrelated to the condition being treated.
  • Dizziness: occasional light‑headedness or vertigo.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: ulceration or hemorrhage, especially with prolonged use.
  • Renal impairment: reduced kidney function or acute renal failure.
  • Allergic reactions: rash, itching, swelling, or anaphylaxis in hypersensitive individuals.

Precautions & Warnings

Before using ibuprofen, consider the following safety measures.

  • Assess renal function: avoid use in severe kidney disease without medical supervision.
  • Evaluate cardiovascular risk: limit use in patients with uncontrolled hypertension or heart disease.
  • Review gastrointestinal history: caution in those with a history of ulcers or bleeding.
  • Monitor pregnancy status: avoid in the third trimester and consult a physician during pregnancy.
  • Check concomitant medications: avoid combining with other NSAIDs or anticoagulants without guidance.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Ibuprofen can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal protective effects.
  • Diuretics: potential for reduced diuretic efficacy and kidney function.
  • Lithium: ibuprofen may raise lithium levels, necessitating serum monitoring.

Frequently Asked Questions

Nurofen contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and treat inflammation associated with conditions such as headache, dental pain, musculoskeletal aches, and arthritis.

Ibuprofen works by blocking the cyclooxygenase (COX‑1 and COX‑2) enzymes, which reduces the production of prostaglandins. Lower prostaglandin levels diminish pain signaling, lower fever, and decrease inflammation at the site of injury or disease.

The appropriate dose of Nurofen is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and any relevant medical history. Patients should follow the prescriber’s instructions and the product label.

Ibuprofen is generally avoided during the third trimester of pregnancy because it may affect fetal circulation. It should be used in pregnancy only if clearly needed and prescribed by a doctor. While short‑term use during breastfeeding is considered low risk, a healthcare provider should be consulted.

To order Nurofen, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with acetaminophen, ibuprofen (Nurofen) offers both analgesic and anti‑inflammatory effects, making it suitable for conditions where inflammation is a component. Unlike stronger opioids, it has a lower risk of dependence but shares typical NSAID cautions such as gastrointestinal and renal considerations.

Nurofen tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and direct sunlight. Keep the container tightly closed and out of reach of children.

Nurofen is taken orally with a glass of water. It can be taken with or without food, although taking it with food may reduce stomach irritation. The exact administration schedule should follow the prescriber’s guidance.

Serious risks include gastrointestinal bleeding or ulceration, especially with prolonged use, as well as renal impairment and severe allergic reactions such as anaphylaxis. Patients with a history of ulcers, kidney disease, or cardiovascular conditions should discuss risks with their healthcare provider.

Nurofen should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding, severe heart failure, or advanced kidney disease. It is also contraindicated in the third trimester of pregnancy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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