Product image of Nurofen (Ibuprofen) supplied by GNH India

Nurofen

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a Nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It treats mild to moderate pain, reduces fever, and alleviates inflammation in adults and children when appropriate.

GNH India supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Nordic A/S

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Indications & Clinical Uses

Nurofen, an ibuprofen‑based NSAID, is indicated for conditions involving pain, fever, or inflammation.

  • Pain relief: reduces mild to moderate pain such as headache, dental or musculoskeletal discomfort.
  • Fever reduction: lowers elevated body temperature associated with infections or inflammatory states.
  • Inflammation: diminishes swelling and stiffness in conditions like arthritis or minor injuries.

How It Works

  • Ibuprofen inhibits cyclooxygenase enzymes COX‑1 and COX‑2, decreasing the synthesis of prostaglandins that mediate pain, fever, and inflammation. By reducing prostaglandin levels at sites of tissue injury, it provides analgesic, antipyretic, and anti‑inflammatory effects without directly acting on the central nervous system.

Side Effects

Common Side Effects

  • Stomach upset or heartburn
  • Nausea or mild vomiting
  • Dizziness or headache
  • Mild skin rash or itching

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe allergic reaction (anaphylaxis)
  • Kidney function impairment
  • Elevated liver enzymes or hepatic injury
  • Cardiovascular events such as heart attack or stroke
  • Blood disorders including thrombocytopenia

Precautions & Warnings

Before using Nurofen, consider the following precautions:

  • Known hypersensitivity: avoid if allergic to ibuprofen or other NSAIDs.
  • Gastrointestinal ulcer disease: use with caution and monitor for bleeding.
  • Renal impairment: adjust use and monitor kidney function.
  • Cardiovascular disease: assess risk of thrombotic events.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines. Review the following categories:

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • ACE inhibitors (e.g., enalapril): may reduce renal function.

Moderate Interactions (Monitor Closely)

  • Diuretics (e.g., furosemide): potential reduction in diuretic efficacy.
  • Selective serotonin reuptake inhibitors (e.g., sertraline): may increase bleeding tendency.

Frequently Asked Questions

Nurofen is an over‑the‑counter medication that contains ibuprofen, a nonsteroidal anti‑inflammatory drug. It is used to relieve mild to moderate pain, lower fever, and reduce inflammation caused by conditions such as headaches, dental pain, muscle aches, arthritis, and common colds.

Ibuprofen works by blocking the cyclooxygenase‑1 and cyclooxygenase‑2 (COX‑1 and COX‑2) enzymes. This inhibition reduces the production of prostaglandins, which are chemical messengers that cause pain, fever, and inflammation at the site of tissue injury.

The appropriate dose of Nurofen is determined by a prescriber or healthcare professional based on the patient’s age, weight, medical condition, and the severity of symptoms. The product label provides dosing ranges, but the final regimen should always follow professional guidance.

Safety of ibuprofen during pregnancy and lactation is not fully established. It is generally avoided in the third trimester because of potential fetal risks. Breastfeeding mothers should consult a healthcare provider before using Nurofen, as ibuprofen can pass into breast milk in small amounts.

To order Nurofen, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Both Nurofen (ibuprofen) and acetaminophen relieve pain and reduce fever, but they belong to different drug classes. Ibuprofen also has anti‑inflammatory properties and can affect platelet function, while acetaminophen lacks significant anti‑inflammatory action and has a lower risk of gastrointestinal irritation. Choice depends on the clinical situation and patient tolerance.

Nurofen tablets should be stored at ambient temperature, below 25 °C, in their original packaging to protect them from moisture and light. Keep the container tightly closed and out of reach of children. Do not store in bathrooms or near heat sources.

Nurofen is taken orally with a glass of water. It can be taken with or without food, although taking it with food or milk may reduce stomach upset. Swallow the tablet whole; do not crush or chew unless the product specifically allows it.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, kidney injury, liver dysfunction, and increased cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they experience signs of these conditions.

Nurofen should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe renal or hepatic impairment, uncontrolled hypertension, or a history of cardiovascular disease without medical advice. Pregnant women in the third trimester and children under the recommended age should also not use it without professional guidance.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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