Product image of Nurofen (Ibuprofen) supplied by GNH India

Nurofen

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It reduces pain, fever, and inflammation and is commonly used in adults and children for short‑term symptom relief. Its anti‑inflammatory action makes it suitable for conditions such as headache, dental pain, muscular aches, and fever associated with common colds.

GNH India supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, clinics and procurement teams worldwide.

Manufacturer / TM Owner

Reckitt Benckiser (Poland) S.A.

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Indications & Clinical Uses

Ibuprofen acts as a non‑selective cyclooxygenase inhibitor to relieve pain, fever and inflammation.

  • Headache: relief of mild to moderate headache symptoms.
  • Dental pain: reduction of toothache and postoperative dental discomfort.
  • Musculoskeletal pain: alleviation of back, joint and muscle aches.
  • Fever: lowering of elevated body temperature associated with infections.
  • Menstrual cramps: easing of dysmenorrhea related discomfort.

How It Works

  • Ibuprofen exerts its effect by non‑selectively inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which decreases the conversion of arachidonic acid to prostaglandins. The reduced prostaglandin synthesis leads to diminished inflammation, pain signaling, and fever generation at the site of tissue injury or infection.

Side Effects

Common Side Effects

  • Stomach upset or dyspepsia.
  • Nausea or mild vomiting.
  • Heartburn or acid reflux.
  • Dizziness or light‑headedness.
  • Headache.
  • Diarrhoea.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reactions such as anaphylaxis or skin rash.
  • Liver injury indicated by jaundice or elevated enzymes.
  • Kidney impairment or acute renal failure.
  • Cardiovascular events including heart attack or stroke.
  • Blood disorders such as thrombocytopenia.

Precautions & Warnings

Before using Nurofen, consider the following precautions:

  • Assess renal function: avoid in severe renal impairment.
  • Known hypersensitivity: do not use if allergic to ibuprofen or other NSAIDs.
  • Asthma caution: may exacerbate bronchospasm in aspirin‑sensitive patients.
  • Alcohol consumption: limit intake as it increases gastrointestinal risk.
  • Duration of use: do not exceed recommended short‑term periods to reduce ulcer risk.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen may interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Corticosteroids: additive risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely):\n- ACE inhibitors or ARBs: possible reduction in antihypertensive effect and renal function.

  • Lithium: ibuprofen can raise lithium serum levels.
  • Methotrexate: reduced clearance may lead to toxicity.

Frequently Asked Questions

Nurofen contains ibuprofen, an NSAID that is used to relieve mild to moderate pain, reduce fever, and decrease inflammation. It is commonly employed for headaches, dental pain, muscular aches, fever associated with infections, and menstrual cramps.

Ibuprofen works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which reduces the synthesis of prostaglandins. Lower prostaglandin levels diminish pain signaling, lower body temperature, and lessen inflammatory responses.

The appropriate dose of Nurofen is determined by a prescriber or according to the product label. Dosage depends on the patient's age, weight, clinical condition, and local regulatory guidance, and should never exceed the recommended maximum.

Ibuprofen is generally avoided during the third trimester of pregnancy because it may affect fetal cardiovascular function. Use during early pregnancy or while breastfeeding should be discussed with a healthcare professional, who can weigh potential benefits against risks.

To order Nurofen, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nurofen (ibuprofen) shares the same class mechanism as other NSAIDs such as naproxen or diclofenac, but it has a relatively short half‑life and a well‑established safety profile for short‑term use. Choice among NSAIDs often depends on individual tolerability, dosing frequency, and specific clinical considerations.

Nurofen tablets should be stored at room temperature, below 25 °C, in their original packaging to protect from moisture and light. Keep the product out of reach of children and do not use after the expiry date.

Nurofen is taken orally with a glass of water. It can be taken with or without food, although taking it with food or milk may reduce stomach irritation. Swallow tablets whole; do not crush or chew unless the product specifically allows it.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, kidney injury, liver toxicity, and increased cardiovascular events like heart attack or stroke, especially with prolonged or high‑dose use.

Nurofen should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, severe renal or hepatic impairment, and during the third trimester of pregnancy unless advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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