Product image of Nurofen (Ibuprofen) supplied by GNH India

Nurofen

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for systemic use. It is used to relieve pain, reduce fever, and lessen inflammation in a variety of conditions for adults and children when appropriate.

GNH India supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser D.O.O.

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Indications & Clinical Uses

Nurofen (ibuprofen) acts on inflammatory pathways to provide symptomatic relief for several common conditions:

  • Pain: alleviates mild to moderate acute pain such as dental or post‑operative discomfort.
  • Fever: reduces elevated body temperature associated with infections or inflammatory states.
  • Inflammation: diminishes swelling and redness in conditions like sprains or bursitis.
  • Headache: eases tension‑type and migraine‑associated head pain.
  • Musculoskeletal pain: helps manage aches from arthritis, back strain, or over‑use injuries.

How It Works

  • Ibuprofen inhibits cyclooxygenase enzymes COX‑1 and COX‑2, which are key in converting arachidonic acid to prostaglandins. By reducing prostaglandin synthesis, it lowers inflammation, pain signaling, and fever generation throughout the body.

Side Effects

Adverse reactions may occur with ibuprofen use. They are categorized by frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or mild abdominal pain.
  • Headache: transient mild headache.
  • Dizziness: occasional light‑headed sensation.
  • Rash: mild skin erythema or itching.
  • Elevated blood pressure: modest increase in some patients.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe allergic reactions: angioedema, anaphylaxis.
  • Renal impairment: reduced kidney function.
  • Hepatotoxicity: liver enzyme elevations.
  • Cardiovascular events: increased risk of heart attack or stroke in high‑risk individuals.

Precautions & Warnings

When using Nurofen, consider the following safety measures:

  • Contraindications: avoid if you have a known hypersensitivity to ibuprofen or other NSAIDs.
  • Gastrointestinal risk: use with food or an antacid if you have a history of ulcer disease.
  • Cardiovascular caution: limit use in patients with hypertension, heart disease, or stroke risk.
  • Renal monitoring: assess kidney function in those with chronic kidney disease or dehydration.
  • Pregnancy and lactation: consult a healthcare professional before use during pregnancy or breastfeeding.
  • Store at ambient temperature: keep below 25 °C, in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: additive cardiovascular risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: may reduce renal protective effects.
  • Diuretics: potential for decreased kidney perfusion.
  • Lithium: ibuprofen can raise lithium serum levels.
  • Methotrexate: reduced clearance leading to toxicity.
  • SSRIs or other antidepressants: modestly increased bleeding risk.

Frequently Asked Questions

Nurofen contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, lower fever, and reduce inflammation associated with conditions such as headaches, musculoskeletal aches, dental pain, and viral or bacterial infections.

Ibuprofen works by blocking the cyclooxygenase‑1 and cyclooxygenase‑2 (COX‑1 and COX‑2) enzymes, which are essential for the production of prostaglandins. Lower prostaglandin levels result in decreased pain signaling, reduced fever, and diminished inflammatory swelling.

The appropriate dose of Nurofen is determined by a prescriber or pharmacist based on the patient’s age, weight, clinical condition, and local labeling. Always follow the specific dosing instructions provided by the healthcare professional.

Ibuprofen should be used with caution during pregnancy, especially in the third trimester, and only if clearly needed. Breastfeeding mothers should consult a healthcare professional before use, as ibuprofen can be excreted in breast milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with acetaminophen, ibuprofen offers both analgesic and anti‑inflammatory effects, making it more suitable for conditions involving swelling. Compared with stronger NSAIDs like diclofenac, ibuprofen generally has a lower risk of gastrointestinal complications at standard doses.

Store Nurofen tablets at ambient temperature below 25 °C, in the original container, protected from moisture, heat and direct sunlight. Keep out of reach of children and do not use after the expiry date.

Nurofen is intended for oral administration. The tablets should be swallowed whole with a glass of water, preferably with food or a milky drink to minimize gastrointestinal irritation.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, renal impairment, and an increased risk of cardiovascular events like heart attack or stroke, particularly with high‑dose or prolonged use.

Individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant kidney or liver disease should avoid Nurofen unless advised otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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