Product image of Nurofen (Ibuprofen) supplied by GNH India

Nurofen

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a nonsteroidal anti‑inflammatory drug (NSAID) presented as an oral formulation for oral use. It is used to relieve mild to moderate pain, reduce fever, and lessen inflammation in a variety of conditions for adults and children as directed by a healthcare professional.

GNH India supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare (Scandinavia) A/S

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Indications & Clinical Uses

Ibuprofen acts systemically to reduce inflammation and pain through cyclo‑oxygenase inhibition, making it suitable for several common conditions.

  • Headache: provides relief from tension‑type and mild migraine pain.
  • Fever: lowers elevated body temperature associated with infections or inflammatory states.
  • Musculoskeletal pain: eases discomfort from strains, sprains, arthritis and other inflammatory joint conditions.

How It Works

  • Ibuprofen reversibly inhibits both cyclo‑oxygenase‑1 (COX‑1) and cyclo‑oxygenase‑2 (COX‑2) enzymes, decreasing the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis leads to diminished inflammation, pain signalling, and fever generation at peripheral and central sites.

Side Effects

Adverse reactions may range from mild to severe and should be monitored during therapy.

Common Side Effects

  • Gastrointestinal upset: nausea, dyspepsia or abdominal discomfort.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or mild itching.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or perforation.
  • Severe allergic reactions such as anaphylaxis.
  • Acute kidney injury or worsening of chronic renal disease.
  • Hepatotoxicity presenting as elevated liver enzymes.
  • Increased risk of cardiovascular events, especially with long‑term use.

Precautions & Warnings

Before initiating ibuprofen therapy, consider the following safety measures.

  • Assess renal function: avoid or adjust dose in patients with impaired kidney function.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Use with caution in asthma: monitor for bronchospasm.
  • Limit concurrent use with anticoagulants or other NSAIDs to reduce bleeding risk.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can affect the activity of several other medicines; some combinations require avoidance while others need close monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • Other NSAIDs or aspirin: heightened gastrointestinal toxicity.
  • Corticosteroids: synergistic risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • Diuretics and ACE inhibitors: may reduce renal perfusion.
  • Lithium: ibuprofen can raise serum lithium levels, requiring monitoring.

Frequently Asked Questions

Nurofen, containing ibuprofen, is used to relieve mild to moderate pain such as headaches, toothaches, and menstrual cramps, to lower fever, and to reduce inflammation associated with musculoskeletal disorders like arthritis or sports injuries.

Ibuprofen blocks the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which are needed to produce prostaglandins. By lowering prostaglandin levels, it reduces inflammation, diminishes pain‑signal transmission, and helps the body reset its temperature set‑point, thereby lowering fever.

The appropriate dose of Nurofen is determined by a prescriber or pharmacist based on the patient’s age, weight, clinical condition, and local labeling. Patients should follow the specific dosing instructions provided with the product or by their healthcare professional.

Safety of ibuprofen in pregnancy and lactation is not fully established. It is generally avoided in the third trimester and used only if clearly needed under medical supervision. Breastfeeding mothers should consult a healthcare professional before use.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Nurofen (ibuprofen) shares the same class mechanism as other NSAIDs such as naproxen or diclofenac, but it has a relatively short half‑life and is often preferred for its rapid onset and flexible dosing. Individual response and safety profiles may differ, so clinicians choose based on patient factors.

Nurofen should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Nurofen is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce the chance of stomach upset. Swallow tablets whole; do not crush or chew unless the formulation specifically allows it.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, acute kidney injury, and increased cardiovascular events like heart attack or stroke, especially with high‑dose or prolonged use. Patients should seek immediate medical attention if they notice signs of these conditions.

Individuals with known hypersensitivity to ibuprofen or any other NSAID, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or those in the third trimester of pregnancy should avoid Nurofen. A healthcare professional should evaluate suitability for all other patients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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