Nurofen (Ibuprofen)

Ibuprofen belongs to the non‑steroidal anti‑inflammatory drug class and works by non‑selectively inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition blocks the conversion of arachidonic acid to prostaglandins, which are mediators of pain, fever, and inflammation. Reducing prostaglandin levels leads to analgesic, antipyretic, and anti‑inflammatory effects.

The specific dose of Nurofen suppository is determined by the prescribing healthcare professional based on the patient’s age, weight, condition being treated, and overall health status. The prescriber will select the appropriate strength and frequency, and patients should follow that guidance without deviation.

The safety of ibuprofen suppositories in pregnancy and lactation has not been fully established. It is generally advised to avoid ibuprofen during the third trimester and to consult a healthcare provider before using it while pregnant or breastfeeding. The prescriber will weigh potential benefits against possible risks.

To place an order, visit the product page on gnhindia.com and submit an enquiry with the required quantity of Nurofen suppositories. GNH India works with hospitals, pharmacies, and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Nurofen (ibuprofen) offers a well‑characterized safety and efficacy profile comparable to other non‑selective NSAIDs such as naproxen or diclofenac. Its rectal formulation provides an alternative route when oral intake is problematic, and its onset of action is similar to oral ibuprofen, though absorption may be slightly slower.

Nurofen suppositories should be stored at room temperature, preferably below 25 °C, in the original packaging to protect them from moisture and heat. Keep the product out of reach of children and avoid exposure to direct sunlight or extreme temperatures, which could affect stability.

The suppository is inserted rectally, typically after a bowel movement and before lying down. The patient should wash hands, remove any protective wrapper, and gently push the suppository into the rectum using a finger or applicator, ensuring it is placed past the sphincter for optimal absorption.

Serious adverse reactions, though uncommon, include gastrointestinal bleeding or ulceration, severe allergic responses such as anaphylaxis, kidney impairment, and cardiovascular events like myocardial infarction or stroke. Patients should seek immediate medical attention if they experience symptoms such as severe abdominal pain, blood in stool, swelling, or difficulty breathing.

Nurofen should be avoided in individuals with known hypersensitivity to ibuprofen or other NSAIDs, active gastrointestinal ulcers or bleeding, severe renal or hepatic impairment, uncontrolled hypertension, and in the third trimester of pregnancy. Additionally, patients taking anticoagulants, certain antihypertensives, or other NSAIDs should consult a healthcare professional before use.