Product image of Nurofen (Ibuprofen) supplied by GNH India

Nurofen

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen, is a non‑steroidal anti‑inflammatory drug presented as a strength/form for oral use. It treats mild to moderate pain, fever and inflammation in adults and children as directed by a healthcare professional.

GNH India supplies Nurofen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser (Poland) S.A.

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Indications & Clinical Uses

Ibuprofen acts on inflammatory pathways to relieve pain and reduce fever. It is commonly used for:

  • Headache: provides relief from tension‑type and migraine‑associated pain.
  • Dental pain: reduces post‑extraction or procedure discomfort.
  • Musculoskeletal pain: eases aches from sprains, strains and arthritis.
  • Fever: lowers elevated body temperature in acute infections.
  • Menstrual cramps: diminishes dysmenorrhoeic pain.

How It Works

  • Ibuprofen inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing the synthesis of prostaglandins that mediate inflammation, pain and fever. This reduction in prostaglandin levels leads to the drug’s analgesic, antipyretic and anti‑inflammatory effects.

Side Effects

Adverse reactions may range from mild to severe.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or heartburn.
  • Headache: mild, transient headache.
  • Dizziness: occasional light‑headed feeling.
  • Rash: mild skin irritation or erythema.
  • Elevated blood pressure: modest rise in some patients.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration.
  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Renal impairment or acute kidney injury.
  • Anaphylaxis: life‑threatening allergic response.
  • Hepatotoxicity: liver enzyme elevations or injury.

Precautions & Warnings

Before using Nurofen, consider the following safety measures:

  • Cardiovascular risk: avoid if you have a history of heart disease or stroke.
  • Gastrointestinal history: caution in patients with ulcers or chronic gastritis.
  • Renal function: monitor kidney health in those with existing impairment.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Concomitant medications: review all current drugs for potential interactions.
  • Store at ambient temperature: keep below 25°C, in the original packaging, protected from moisture.

Avoid Interactions

Ibuprofen may interact with several drug classes. Review the following:

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • High‑dose aspirin: heightened gastrointestinal toxicity.
  • Selective COX‑2 inhibitors: additive renal and cardiovascular effects.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or ARBs: possible reduction in antihypertensive efficacy.
  • Diuretics: risk of reduced renal perfusion.
  • Lithium: increased serum lithium levels.
  • Methotrexate: decreased renal clearance leading to toxicity.

Frequently Asked Questions

Nurofen contains ibuprofen, an NSAID that is used to relieve mild to moderate pain, reduce fever and lessen inflammation caused by conditions such as headaches, dental pain, musculoskeletal aches, fever and menstrual cramps.

Ibuprofen works by inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which reduces the production of prostaglandins—chemicals that trigger pain, fever and inflammation in the body.

The appropriate dose of Nurofen is determined by a prescriber based on the patient’s age, weight, condition and local prescribing guidelines. Patients should follow the healthcare professional’s instructions and the product label.

Ibuprofen is generally avoided in the third trimester of pregnancy because of potential fetal risks, and it should only be used during pregnancy or lactation if clearly prescribed by a healthcare professional after weighing benefits and risks.

To order Nurofen, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and import documentation.

Nurofen (ibuprofen) offers a balanced profile of analgesic, antipyretic and anti‑inflammatory effects, with a relatively short half‑life compared with drugs like naproxen. It is widely used because of its proven efficacy and availability, though individual response and safety considerations may favor alternative NSAIDs for some patients.

Store Nurofen at ambient temperature, below 25°C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and do not use it after the expiry date.

Nurofen is taken orally, usually with water. It can be swallowed with or without food, although taking it with food may reduce the chance of stomach irritation.

Serious risks include gastrointestinal bleeding or ulceration, severe skin reactions such as Stevens‑Johnson syndrome, kidney injury, and allergic anaphylaxis. Patients should seek immediate medical attention if they experience signs of these conditions.

Individuals with a known allergy to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, or advanced kidney disease should avoid Nurofen unless specifically directed by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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