Product image of Nurofen Laranja (Ibuprofen) supplied by GNH India

Nurofen Laranja

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen Laranja (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Laranja, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as an oral tablet formulation for oral use. It is commonly employed to relieve mild to moderate pain, reduce fever, and alleviate inflammation in adults and children when appropriate. It is indicated for short‑term management of conditions such as headache, dental pain, musculoskeletal discomfort, and menstrual cramps.

GNH India supplies Nurofen Laranja as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company ensures quality, traceability and regulatory compliance across all markets.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare, Lda.

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Indications & Clinical Uses

  • Ibuprofen, an NSAID, reduces pain, fever and inflammation by inhibiting prostaglandin synthesis.
  • Headache: provides relief by decreasing inflammatory mediators in cranial tissues.
  • Fever: lowers body temperature through central thermoregulatory effects.
  • Musculoskeletal pain: alleviates discomfort from strains, sprains and arthritis.
  • Dental pain: reduces postoperative or inflammatory dental discomfort.
  • Dysmenorrhea: eases menstrual cramps by diminishing uterine prostaglandins.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting the cyclooxygenase (COX‑1 and COX‑2) enzymes, which catalyze the conversion of arachidonic acid to prostaglandins and thromboxanes. By lowering prostaglandin production, it diminishes inflammation, pain signalling and fever generation, while preserving platelet function to a lesser extent compared with selective COX‑2 inhibitors.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Stomach upset: nausea, dyspepsia or heartburn.
  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Rash: mild skin irritation or erythema.
  • Diarrhoea: loose stools.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration: potentially life‑threatening.
  • Renal impairment: reduced kidney function or acute failure.
  • Severe allergic reaction: anaphylaxis, angio‑edema or bronchospasm.
  • Liver injury: elevated enzymes or hepatitis.
  • Skin reactions: Stevens‑Johnson syndrome or toxic epidermal necrolysis.

Precautions & Warnings

When prescribing ibuprofen, several safety considerations should be observed to minimise risk.

  • Assess gastrointestinal risk: evaluate history of ulcers or bleeding before use.
  • Monitor renal function: avoid in patients with chronic kidney disease or dehydration.
  • Use the lowest effective dose: limit duration to the shortest necessary period.
  • Avoid in third‑trimester pregnancy: risk of fetal complications.
  • Caution with anticoagulants: increased bleeding tendency.
  • Store at ambient temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Ibuprofen can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened bleeding risk.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: increased ulcer risk.
  • ACE inhibitors or ARBs: possible reduction in renal function.
  • Lithium: elevated serum lithium levels.

Moderate Interactions (Monitor Closely)

  • Diuretics: may reduce renal perfusion.
  • Methotrexate: decreased clearance leading to toxicity.
  • Selective serotonin reuptake inhibitors (SSRIs): modest bleeding risk.
  • Antihypertensives: ibuprofen may blunt blood pressure control.
  • Antidiabetic agents: potential alteration of glucose control.

Frequently Asked Questions

Nurofen Laranja contains ibuprofen, an NSAID that is used to relieve mild to moderate pain, reduce fever, and lessen inflammation. It is commonly prescribed for conditions such as headache, dental pain, musculoskeletal discomfort, and menstrual cramps, providing short‑term symptom control when other measures are insufficient.

Ibuprofen works by reversibly blocking the cyclooxygenase enzymes COX‑1 and COX‑2. This inhibition reduces the conversion of arachidonic acid into prostaglandins, which are key mediators of pain, fever, and inflammation. Lower prostaglandin levels result in decreased pain signalling, reduced fever, and diminished inflammatory swelling.

The exact dose of Nurofen Laranja is determined by the prescribing clinician based on the patient’s age, weight, condition, and overall health status. Healthcare professionals follow established guidelines for ibuprofen, typically selecting the lowest effective dose for the shortest duration needed to achieve therapeutic benefit.

Ibuprofen is generally avoided in the third trimester of pregnancy because it may affect fetal cardiovascular development. During the first and second trimesters, use should be limited and only under medical advice. Ibuprofen passes into breast milk in small amounts; lactating mothers should consult a healthcare provider before use.

To order Nurofen Laranja, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, confirming trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Both ibuprofen (Nurofen Laranja) and naproxen belong to the NSAID class and share similar mechanisms of COX inhibition. Ibuprofen has a shorter half‑life, often requiring multiple daily doses, whereas naproxen provides longer‑lasting relief with fewer doses. Choice between them depends on patient tolerance, dosing convenience and specific safety considerations.

Nurofen Laranja should be stored at ambient temperature, ideally below 25 °C. Keep the tablets in their original packaging to protect them from moisture and light. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Nurofen Laranja is administered orally. The tablet should be swallowed whole with a full glass of water, preferably with food or milk to reduce stomach irritation. Patients should follow the dosing instructions provided by their healthcare professional and avoid crushing or chewing the tablet unless specifically directed.

Serious risks include gastrointestinal bleeding or ulceration, especially in patients with a history of ulcers or who use anticoagulants. Renal impairment can occur, particularly in individuals with pre‑existing kidney disease or dehydration. Rare but severe allergic reactions such as anaphylaxis, as well as liver injury and severe skin reactions, also warrant immediate medical attention.

Nurofen Laranja should be avoided by individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients with severe renal or hepatic impairment, and women in the third trimester of pregnancy. Caution is also advised for patients on anticoagulant therapy or with uncontrolled hypertension.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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