Product image of Nurofen Lysine (Ibuprofen) supplied by GNH India

Nurofen Lysine

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen Lysine (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Lysine, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral tablet for oral use. It is used to relieve pain, reduce fever, and lessen inflammation in adults and children when appropriate.

GNH India supplies Nurofen Lysine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare (Belgium) Sa/Nv

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Indications & Clinical Uses

Ibuprofen acts systemically to modulate inflammatory pathways and is indicated for several common conditions:

  • Pain: provides relief of mild to moderate nociceptive pain such as headache, dental or musculoskeletal discomfort.
  • Fever: lowers elevated body temperature associated with infection or inflammatory states.
  • Inflammation: reduces swelling and tenderness in conditions like arthritis or soft‑tissue injury.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting cyclooxygenase‑1 (COX‑1) and cyclooxygenase‑2 (COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. The resulting decrease in prostaglandin synthesis diminishes peripheral sensitisation, lowers the hypothalamic set‑point for temperature, and curtails inflammatory exudate formation.

Side Effects

Adverse reactions may vary in frequency and severity.

Common Side Effects

  • Nausea: mild gastrointestinal upset that often resolves without intervention.
  • Dyspepsia: discomfort or burning in the upper abdomen.
  • Headache: transient tension‑type headache.
  • Dizziness: occasional light‑headed sensation.
  • Rash: mild skin erythema or itching.
  • Diarrhoea: loose stools that are usually self‑limiting.

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration: may present as black stools or abdominal pain.
  • Renal impairment: reduced urine output or swelling.
  • Severe allergic reaction: hives, swelling of face or throat, difficulty breathing.
  • Liver enzyme elevation: abnormal liver function tests.
  • Stevens‑Johnson syndrome: painful skin blistering and mucosal involvement.
  • Anaphylaxis: rapid onset of systemic allergic symptoms requiring emergency care.

Precautions & Warnings

Before using Nurofen Lysine, consider the following safety measures:

  • Assess gastrointestinal risk: avoid in patients with active ulcers or a history of GI bleeding.
  • Use the lowest effective dose: limit duration to the shortest period needed for symptom control.
  • Avoid in known hypersensitivity: discontinue if allergic reactions occur.
  • Caution in renal or hepatic impairment: monitor kidney and liver function where pre‑existing disease exists.
  • Avoid concomitant anticoagulants: increased risk of bleeding when combined with warfarin or similar agents.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen may interact with other medicines; some combinations require avoidance while others need monitoring.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened risk of serious bleeding.
  • Other NSAIDs or high‑dose aspirin: additive gastrointestinal toxicity.
  • ACE inhibitors (e.g., enalapril): potential reduction in renal function.

Moderate Interactions (Monitor Closely)

  • Diuretics (e.g., furosemide): may diminish diuretic efficacy and affect kidney function.
  • Methotrexate: ibuprofen can increase methotrexate serum levels.
  • Selective serotonin reuptake inhibitors (e.g., sertraline): modestly increased bleeding risk.

Frequently Asked Questions

Nurofen Lysine contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, lower fever, and reduce inflammation associated with conditions such as headaches, dental pain, musculoskeletal aches, and arthritic disorders. It is available over the counter in many European markets for short‑term symptom management.

Ibuprofen works by reversibly blocking the cyclooxygenase‑1 and cyclooxygenase‑2 enzymes, which are essential for the production of prostaglandins. By reducing prostaglandin synthesis, ibuprofen diminishes the inflammatory response, lowers the hypothalamic set‑point for body temperature, and decreases the sensitivity of pain receptors.

The appropriate dose of Nurofen Lysine is determined by a qualified prescriber or according to the product’s labeling. Dosage depends on factors such as the patient’s age, weight, the severity of symptoms, and any existing medical conditions. Always follow the healthcare professional’s instructions or the information provided on the package.

Ibuprofen is generally avoided during the third trimester of pregnancy because it may affect fetal cardiovascular function. For earlier stages, it should only be used if clearly needed and after consulting a healthcare provider. While small amounts are excreted in breast milk, mothers should discuss use with a physician to weigh benefits against potential risks.

To place an order, visit the product page on gnhindia.com and submit an enquiry with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials. The sales team then replies with pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Nurofen Lysine delivers ibuprofen, which has a well‑established efficacy and safety profile comparable to other NSAIDs such as naproxen or diclofenac. Ibuprofen’s relatively short half‑life often allows for flexible dosing, but it may have a slightly higher risk of gastrointestinal irritation than selective COX‑2 inhibitors. Choice of NSAID should be individualized based on patient tolerance, comorbidities, and physician guidance.

Store Nurofen Lysine tablets at ambient temperature, ideally below 25 °C. Keep the product in its original packaging to protect it from moisture and direct sunlight. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Nurofen Lysine is taken orally with a full glass of water. It may be taken with or without food; however, taking it with food can help minimise gastrointestinal discomfort. Swallow the tablet whole; do not crush or chew unless the product label specifically permits it.

Serious risks include gastrointestinal bleeding or ulceration, especially with prolonged use or in patients with a history of GI disease. Renal impairment can occur, particularly in individuals with pre‑existing kidney problems or dehydration. Rare but severe allergic reactions such as anaphylaxis, Stevens‑Johnson syndrome, or severe skin reactions also require immediate medical attention.

Individuals with known hypersensitivity to ibuprofen or any other NSAIDs should avoid Nurofen Lysine. It is also contraindicated in patients with active gastrointestinal bleeding, severe heart failure, or those who have had a recent coronary artery bypass graft. Pregnant women in the third trimester and patients taking certain anticoagulants or other NSAIDs should consult a healthcare professional before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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