Product image of Nurofen Orange, (Ibuprofen) supplied by GNH India

Nurofen Orange,

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen Orange, (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Orange, is a nonsteroidal anti-inflammatory drug (NSAID) presented as an oral formulation for oral use. It treats pain, fever and inflammation in adults and children when taken as directed.

GNH India supplies Nurofen Orange as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser (Poland) S.A.

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Indications & Clinical Uses

Ibuprofen is an NSAID that reduces pain, fever and inflammation by inhibiting prostaglandin synthesis.

  • Pain: provides relief of mild to moderate pain such as headache, toothache or muscular discomfort.
  • Fever: lowers elevated body temperature associated with infections or inflammatory conditions.
  • Inflammation: alleviates swelling and discomfort in conditions like arthritis or minor injuries.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting cyclooxygenase (COX‑1 and COX‑2) enzymes, which are essential for the conversion of arachidonic acid to prostaglandins. Reduced prostaglandin synthesis diminishes inflammation, lowers fever, and lessens the perception of pain at peripheral nerve endings.

Side Effects

Common Side Effects

  • Stomach upset or dyspepsia
  • Heartburn or acid reflux
  • Nausea or vomiting
  • Dizziness or light‑headedness
  • Headache
  • Skin rash or itching

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulcer formation
  • Severe allergic reactions including anaphylaxis
  • Kidney impairment or reduced renal function
  • Elevated liver enzymes or hepatic injury
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Blood disorders like thrombocytopenia

Precautions & Warnings

Before using ibuprofen, consider the following precautions:

  • Medical History Review: assess for existing ulcers, kidney disease, heart disease, asthma, or bleeding disorders.
  • Concomitant NSAIDs: avoid using with other NSAIDs to reduce gastrointestinal risk.
  • Alcohol Consumption: limit alcohol as it may increase stomach irritation and bleeding.
  • Dose Minimisation: use the lowest effective dose for the shortest duration needed.
  • Storage: Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen may interact with several medicines. Review the following groups:

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of serious bleeding.
  • ACE inhibitors (e.g., enalapril): may reduce renal function.
  • Lithium: ibuprofen can raise lithium serum levels.
  • Methotrexate: risk of heightened toxicity.
  • SSRIs (e.g., fluoxetine): additive bleeding risk.

Moderate Interactions (Monitor Closely)

  • Diuretics (e.g., furosemide): may lessen diuretic effectiveness.
  • Beta‑blockers (e.g., metoprolol): possible reduction in antihypertensive effect.
  • Caffeine: may increase nervous system side effects.
  • Alcohol: enhances gastrointestinal irritation.
  • Combined NSAID use: additive toxicity and ulcer risk.

Frequently Asked Questions

Nurofen Orange contains ibuprofen, an NSAID that is commonly used to relieve mild to moderate pain, reduce fever, and lessen inflammation associated with conditions such as headaches, dental pain, muscular aches, arthritis, and common colds.

Ibuprofen works by blocking the activity of cyclooxygenase enzymes (COX‑1 and COX‑2). This inhibition reduces the production of prostaglandins, which are chemicals that promote inflammation, pain, and fever, thereby providing symptomatic relief.

The appropriate dose of Nurofen Orange is determined by a qualified prescriber based on the patient’s age, weight, medical condition, and response to therapy. Dosage instructions are provided on the product label and should be followed exactly.

Ibuprofen is generally not recommended during the third trimester of pregnancy due to potential fetal risks. Women who are pregnant, planning to become pregnant, or breastfeeding should consult their healthcare professional before using Nurofen Orange.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Nurofen Orange (ibuprofen) offers a balance of analgesic, antipyretic, and anti‑inflammatory effects with a relatively short half‑life, allowing flexible dosing. Compared with aspirin, it has a lower risk of gastric irritation, while compared with naproxen, it may require more frequent dosing but has a quicker onset of action.

Store Nurofen Orange at room temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Nurofen Orange is taken orally, usually with a full glass of water. It can be taken with or without food, although taking it with food may reduce the chance of stomach discomfort.

Serious risks include gastrointestinal bleeding or ulcer formation, severe allergic reactions such as anaphylaxis, kidney impairment, and rare but serious skin reactions like Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they notice signs of these conditions.

Individuals with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment should avoid using Nurofen Orange unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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