Product image of Nurofen Pain Relief (Ibuprofen) supplied by GNH India

Nurofen Pain Relief

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen Pain Relief (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Pain Relief, is a non‑steroidal anti‑inflammatory drug presented as a tablet for oral use. It treats mild to moderate pain, fever and inflammation in adults and children as directed. It is commonly used for headaches, dental discomfort, musculoskeletal aches, and menstrual cramps.

GNH India supplies Nurofen Pain Relief as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser (Healthcare) Uk Ltd

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Indications & Clinical Uses

Ibuprofen, a non‑steroidal anti‑inflammatory drug, reduces inflammation and pain across several common conditions.

  • Headache: provides relief from tension‑type and migraine‑associated pain.
  • Dental pain: alleviates discomfort following procedures or toothache.
  • Musculoskeletal pain: reduces soreness from strains, sprains and arthritis.
  • Fever: lowers elevated body temperature in acute infections.
  • Menstrual cramps: eases dysmenorrhea associated uterine contractions.

How It Works

  • Ibuprofen exerts its effect by reversibly inhibiting cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, which decreases the synthesis of prostaglandins involved in pain signalling, inflammation and fever. The reduced prostaglandin levels lower peripheral sensitisation of nociceptors and diminish the inflammatory response, resulting in analgesic, antipyretic and anti‑inflammatory actions. By limiting prostaglandin‑mediated vasodilation and edema, ibuprofen also contributes to reduced swelling and improved tissue comfort.

Side Effects

Ibuprofen may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

  • Nausea: mild stomach upset.
  • Dyspepsia: indigestion or heartburn.
  • Headache: occasional recurrence.
  • Dizziness: transient light‑headedness.

Serious or Rare Side Effects

  • Gastrointestinal bleeding: black stools or vomiting blood.
  • Renal impairment: reduced urine output or swelling.
  • Severe allergic reaction: swelling of face, lips, or throat.

Precautions & Warnings

When using ibuprofen, consider the following safety measures.

  • Assess renal function: avoid in patients with severe kidney disease.
  • Avoid use in third trimester: risk of fetal complications.
  • Use cautiously in asthma: may trigger bronchospasm.
  • Do not combine with other NSAIDs: increased risk of GI toxicity.
  • Monitor blood pressure: NSAIDs can elevate BP.
  • Store at ambient temperature: keep in original pack, protect from moisture.

Avoid Interactions

Ibuprofen can interact with several medicines; review the following categories.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Other NSAIDs or aspirin: additive gastrointestinal toxicity.
  • Corticosteroids: heightened ulcer risk.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors: may reduce renal function.
  • Diuretics: potential for decreased kidney perfusion.
  • Lithium: ibuprofen can raise lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Nurofen Pain Relief contains ibuprofen and is indicated for the temporary relief of mild to moderate pain such as headache, dental discomfort, muscle aches, joint pain, and menstrual cramps. It is also used to reduce fever associated with common infections.

Ibuprofen works by reversibly blocking the cyclo‑oxygenase enzymes COX‑1 and COX‑2. This inhibition reduces the production of prostaglandins, which are mediators of pain, inflammation and fever, thereby providing analgesic, antipyretic and anti‑inflammatory effects.

The appropriate dose of ibuprofen is determined by a qualified prescriber based on the patient’s age, weight, clinical condition and response to therapy. Dosage instructions are provided on the prescription label and should be followed exactly.

Ibuprofen should be avoided in the third trimester of pregnancy because it may affect fetal cardiovascular development. During the first and second trimesters, use only if clearly needed and prescribed. It is excreted in breast‑milk; short‑term use is generally considered compatible with breastfeeding, but a healthcare professional should be consulted.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Both ibuprofen (Nurofen) and paracetamol are effective for mild to moderate pain, but ibuprofen additionally offers anti‑inflammatory and antipyretic actions. Paracetamol lacks significant anti‑inflammatory activity and is generally gentler on the stomach, whereas ibuprofen may cause gastrointestinal irritation but provides stronger relief for inflammatory pain.

Store Nurofen tablets at ambient temperature, preferably below 25 °C. Keep the product in its original packaging to protect it from moisture and light. Do not store in a bathroom or near a heat source, and keep out of reach of children.

Nurofen is supplied as oral tablets that should be swallowed whole with a full glass of water. It can be taken with or without food; taking it with food or milk may reduce stomach upset. Do not crush, chew, or dissolve the tablets unless specifically instructed by a healthcare professional.

Serious risks include gastrointestinal bleeding or ulceration, especially with high doses or prolonged use; renal impairment that may manifest as reduced urine output or swelling; and severe allergic reactions such as angio‑edema or anaphylaxis. Prompt medical attention is required if any of these symptoms occur.

Ibuprofen is contraindicated in individuals with known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding or ulcer disease, patients in the third trimester of pregnancy, and people with severe uncontrolled heart failure or severe renal impairment. Consultation with a healthcare provider is essential before use in these groups.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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