Nurofen Pour Enfants (Ibuprofen)

Nurofen Pour Enfants contains ibuprofen, an NSAID that acts on inflammatory pathways to relieve discomfort in paediatric patients.

• Fever: helps lower elevated body temperature in children.
• Headache: eases mild to moderate headache pain.
• Dental pain: reduces pain associated with teething or dental procedures.
• Musculoskeletal pain: alleviates minor strains, sprains and bruises.
• Cold‑like symptoms: provides symptomatic relief of aches associated with viral upper respiratory infections.

• Ibuprofen inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing the synthesis of prostaglandins that mediate inflammation, pain and fever. This reduction in prostaglandin levels leads to the antipyretic and analgesic effects observed in treated patients.

Ibuprofen may produce a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

• Stomach upset
• Nausea
• Diarrhea
• Mild headache
• Dizziness
• Rash

Serious or Rare Side Effects

• Gastrointestinal bleeding
• Severe allergic reaction (anaphylaxis)
• Liver enzyme elevation
• Kidney function impairment
• Stevens‑Johnson syndrome
• Blood clotting abnormalities

When using ibuprofen‑containing products, certain safety measures should be observed.

• Age restriction: not recommended for infants younger than 3 months.
• Allergic history: avoid if the child has known hypersensitivity to ibuprofen or other NSAIDs.
• Gastro‑intestinal risk: use cautiously in children with a history of ulcers or bleeding.
• Renal considerations: monitor hydration status in children with kidney concerns.
• Concomitant medications: review all other medicines for potential NSAID interactions.
• Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Ibuprofen can affect the activity of several other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

• Anticoagulants (e.g., warfarin): increased bleeding risk.
• High‑dose aspirin aspirin: heightened gastrointestinal toxicity.
• Certain antihypertensives (ACE‑inhibitors, ARBs): may reduce blood‑pressure control.

Moderate Interactions (Monitor Closely)

• Diuretics: possible reduction in renal clearance.
• Lithium: ibuprofen may raise lithium serum levels.
• Methotrexate: potential increase in toxicity.
• Selective serotonin reuptake inhibitors (SSRIs): elevated bleeding risk.
• Corticosteroids: additive gastrointestinal irritation.