Product image of Nurofen Rhume (Pseudoephedrine Hydrochloride, Ibuprofen) supplied by GNH India

Nurofen Rhume

Active Ingredient:
Pseudoephedrine Hydrochloride, Ibuprofen
Origin:
EU

Nurofen Rhume (Pseudoephedrine Hydrochloride, Ibuprofen)

Ibuprofen and Pseudoephedrine Hydrochloride, the active ingredient in Nurofen Rhume, is a nonsteroidal anti‑inflammatory drug (NSAID) and sympathomimetic decongestant presented as an oral formulation for over‑the‑counter use. It provides analgesic, antipyretic and nasal decongestant effects for adults experiencing cold‑related symptoms.

GNH India supplies Nurofen Rhume as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare France

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Indications & Clinical Uses

Nurofen Rhume, combining an NSAID with a sympathomimetic decongestant, is used to manage symptoms of upper respiratory infections and mild pain.

  • Nasal congestion (cold or flu): reduces swelling of nasal mucosa to improve airflow.
  • Headache or toothache: relieves mild to moderate pain.
  • Fever: lowers elevated body temperature.

How It Works

  • Ibuprofen inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, decreasing prostaglandin synthesis and thereby producing analgesic, antipyretic and anti‑inflammatory effects. Pseudoephedrine hydrochloride stimulates α‑adrenergic receptors in the nasal mucosa, causing vasoconstriction that reduces mucosal edema and eases nasal congestion.

Side Effects

Nurofen Rhume may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia, or abdominal pain.
  • Dizziness or headache: mild vertigo or throbbing sensation.
  • Insomnia or nervousness: difficulty sleeping or feeling jittery.

Serious or Rare Side Effects

  • Allergic reactions: rash, itching, swelling, or anaphylaxis.
  • Cardiovascular events: increased blood pressure or palpitations.
  • Gastrointestinal bleeding: vomiting blood or black stools.

Precautions & Warnings

When considering Nurofen Rhume, several safety precautions should be observed.

  • Contraindicated in: known hypersensitivity to ibuprofen, pseudoephedrine, or other NSAIDs.
  • Avoid in: patients with uncontrolled hypertension, severe heart disease, or hyperthyroidism.
  • Use cautiously in: individuals with asthma, renal impairment, or gastric ulcer history.
  • Do not combine with: other NSAIDs, monoamine oxidase inhibitors, or certain antidepressants without medical advice.
  • Pregnancy and breastfeeding: consult a healthcare professional before use.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and keep in original packaging.

Avoid Interactions

Nurofen Rhume can interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Selective serotonin reuptake inhibitors (SSRIs) or SNRIs: heightened bleeding risk.
  • Other sympathomimetic decongestants: excessive cardiovascular stimulation.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: possible reduction in antihypertensive effect.
  • Lithium: pseudoephedrine may raise lithium levels.
  • Methotrexate: ibuprofen can reduce renal clearance, increasing toxicity.

Frequently Asked Questions

Nurofen Rhume is an over‑the‑counter medication that combines ibuprofen and pseudoephedrine to relieve mild to moderate pain, reduce fever, and alleviate nasal congestion associated with colds or flu in adults.

Ibuprofen blocks cyclooxygenase enzymes, lowering prostaglandin production and providing analgesic, antipyretic and anti‑inflammatory effects. Pseudoephedrine activates α‑adrenergic receptors in nasal blood vessels, causing vasoconstriction that reduces swelling and eases breathing.

The appropriate dose is determined by a healthcare professional based on the individual's age, weight and clinical condition. Patients should follow the prescriber’s instructions and the product label without exceeding the recommended amount.

Safety in pregnancy and lactation has not been fully established. Women who are pregnant, planning pregnancy, or breastfeeding should consult their physician before using Nurofen Rhume to weigh potential benefits against risks.

Enquiries can be submitted on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with single‑ingredient ibuprofen or pseudoephedrine products, Nurofen Rhume offers combined pain relief, fever reduction and decongestion in one dose. Alternatives such as Advil Cold & Sinus contain similar ingredients but may differ in strength, formulation or regulatory status in specific markets.

Store the tablets at ambient temperature, preferably below 25 °C. Keep the container tightly closed, protect from moisture and light, and retain the product in its original packaging until use.

Nurofen Rhume is taken orally with a glass of water. The tablets should be swallowed whole and not chewed or crushed, unless otherwise directed by a healthcare professional.

Serious risks include severe allergic reactions (e.g., anaphylaxis), gastrointestinal bleeding or ulceration, and cardiovascular events such as elevated blood pressure or arrhythmias, especially in patients with pre‑existing heart conditions.

Individuals with known hypersensitivity to ibuprofen, pseudoephedrine or any NSAID, those with uncontrolled hypertension, severe heart disease, hyperthyroidism, or who are taking monoamine oxidase inhibitors should avoid using Nurofen Rhume.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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