Nurofen Sinus & Blocked Nose (Phenylephrine Hydrochloride, Ibuprofen)

Nurofen Sinus & Blocked Nose combines the analgesic and anti‑inflammatory actions of ibuprofen with the decongestant effect of phenylephrine to address upper‑respiratory discomfort. It is indicated for:

• Sinus headache: alleviates pain associated with sinus pressure.
• Nasal congestion: reduces swelling of nasal mucosa to improve airflow.
• Common cold symptoms: eases pain and congestion accompanying viral upper‑respiratory infections.

• Ibuprofen inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing prostagtablet prostaglandin synthesis and thereby reducing inflammation and pain. Phenylephrine hydrochloride acts as an α‑adrenergic receptor agonist, causing vasoconstriction of the nasal mucosal vessels, which diminishes edema and opens the nasal airway.

Side effects may occur with any medication and vary in frequency.

Common Side Effects

• Nausea or upset stomach
• Heartburn or dyspepsia
• Dizziness or light‑headed feeling
• Headache
• Mild insomnia
• Nasal dryness

Serious or Rare Side Effects

• Severe allergic reaction (anaphylaxis, swelling of face or throat)
• Gastrointestinal bleeding or ulceration
• Elevated blood pressure or hypertensive crisis
• Liver enzyme abnormalities
• Kidney function impairment
• Severe skin reactions such as Stevens‑Johnson syndrome

When using Nurofen Sinus & Blocked Nose, consider the following safety measures:

• Assess contraindications: avoid if you have known allergic reactions to ibuprofen or phenylephrine.
• Review cardiovascular risk: patients with hypertension or heart disease may need monitoring.
• Evaluate renal function: caution in individuals with reduced kidney function.
• Monitor gastrointestinal health: those with a history of ulcers should use with care.
• Avoid concurrent use of other NSAIDs or decongestants to reduce additive risk.
• Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Potential drug‑drug interactions should be reviewed before starting therapy.

Major Interactions (Avoid)

• Anticoagulants (e.g., warfarin) – increased risk of bleeding.
• Selective serotonin reuptake inhibitors (SSRIs) – heightened bleeding risk.
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