Product image of Nurofen Voor Kinderen Sinaasappel (Ibuprofen) supplied by GNH India

Nurofen Voor Kinderen Sinaasappel

Active Ingredient:
Ibuprofen
Origin:
EU

Nurofen Voor Kinderen Sinaasappel (Ibuprofen)

Ibuprofen, the active ingredient in Nurofen Voor Kinderen Sinaasappel, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a pediatric oral formulation for children. It reduces fever and alleviates mild to moderate pain in young patients.
GNH India supplies Nurofen Voor Kinderen Sinaasappel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reckitt Benckiser Healthcare B.V.

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Indications & Clinical Uses

  • Ibuprofen, an NSAID, reduces inflammation, pain and fever in several pediatric conditions.
  • Fever: Lowers elevated body temperature in children.
  • Pain: Relieves mild to moderate pain such as headache, toothache, sore throat or musculoskeletal discomfort.
  • Inflammation: Decreases inflammation associated with minor injuries or juvenile arthritis.

How It Works

  • Ibuprofen inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing the synthesis of prostaglandins that mediate inflammation, pain and fever. By reducing prostaglandin levels, it attenuates peripheral sensitisation of nociceptors and lowers the hypothalamic set‑point for temperature regulation.

Side Effects

Adverse reactions may occur with ibuprofen use in children.

Common Side Effects

  • Stomach upset or abdominal discomfort
  • Nausea or vomiting
  • Diarrhoea
  • Mild rash or itching
  • Headache
  • Drowsiness

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe allergic reactions including anaphylaxis
  • Liver enzyme elevation or hepatitis
  • Acute kidney injury or reduced renal function
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Blood dyscrasias such as thrombocytopenia

Precautions & Warnings

  • When using ibuprofen in pediatric patients, several safety considerations apply.
  • Age: Use only in children as directed by a qualified healthcare professional.
  • Dosage: Follow prescriber instructions; do not exceed the recommended amount.
  • Allergy: Avoid if the child has known hypersensitivity to ibuprofen or other NSAIDs.
  • Medical conditions: Exercise caution in children with asthma, renal, hepatic or bleeding disorders.
  • Drug interactions: Review all concomitant medicines with the prescriber.
  • Store at ambient temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Ibuprofen can interact with several medicines; awareness of the interaction level helps manage risk.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Concurrent use of other NSAIDs: additive gastrointestinal toxicity.
  • Systemic corticosteroids: heightened ulcer risk.

Moderate Interactions (Monitor Closely)

  • Selective serotonin reuptake inhibitors (SSRIs): may increase bleeding tendency.
  • Lithium: ibuprofen can raise lithium serum concentrations.
  • Diuretics (e.g., thiazides): may reduce renal clearance of ibuprofen, affecting kidney function.

Frequently Asked Questions

Nurofen Voor Kinderen Sinaasappel is a pediatric ibuprofen product indicated for the temporary relief of fever and mild to moderate pain in children, such as headache, toothache, sore throat, or discomfort from minor injuries.

Ibuprofen blocks the cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, which reduces the production of prostaglandins. Lower prostaglandin levels diminish inflammation, lower pain signals, and reset the hypothalamic temperature set‑point, thereby relieving fever.

The exact dose is determined by the prescribing healthcare professional based on the child’s age, weight, and clinical need. Caregivers should follow the prescriber’s instructions and use the provided measuring device for accurate dosing.

Ibuprofen is generally not recommended for use in pregnant women, especially in the third trimester, and should be used with caution while breastfeeding. Parents should consult a physician before giving the product to a nursing infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and necessary import documentation.

The primary alternative for pediatric fever and pain is paracetamol (acetaminophen). Ibuprofen provides anti‑inflammatory benefits in addition to analgesic and antipyretic effects, whereas paracetamol lacks significant anti‑inflammatory activity. Choice depends on the clinical scenario and individual tolerance.

Store the product at ambient temperature, preferably below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight and children’s reach. Do not freeze; if the liquid appears separated, discard it.

The medication is given orally. Use the calibrated dosing spoon or syringe supplied with the product to measure the exact amount prescribed, and administer it directly into the child’s mouth.

Serious adverse events include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis, acute kidney injury, and rare skin conditions like Stevens‑Johnson syndrome. If any of these occur, seek immediate medical attention.

Children with a known hypersensitivity to ibuprofen or other NSAIDs, those with active gastrointestinal bleeding, severe renal or hepatic impairment, or certain clotting disorders should avoid this product. Consultation with a healthcare professional is essential before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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