Product image of Nutriflex Lipid 32/64/40 Perifer (Valine, Alanine, Arginine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, Threonin) supplied by GNH India

Nutriflex Lipid 32/64/40 Perifer

Active Ingredient:
Valine, Alanine, Arginine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, Threonin
Origin:
EU

Nutriflex Lipid 32/64/40 Perifer (Valine, Alanine, Arginine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, Threonin)

Valine, the active ingredient in Nutriflex Lipid 32/64/40 Perifer, is a branched‑chain amino acid presented as a sterile lipid emulsion for parenteral use. It supports metabolic needs and membrane synthesis in patients requiring intravenous nutrition.

GNH India supplies Nutriflex Lipid 32/64/40 Perifer as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals and transplant centres worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Nutriflex Lipid 32/64/40 Perifer provides parenteral lipid nutrition for patients with increased metabolic demand or impaired oral intake.

  • Post‑operative recovery: supplies essential fatty acids to support wound healing and energy needs.
  • Severe malnutrition: delivers calories and essential lipids when enteral feeding is not feasible.
  • Long‑term parenteral nutrition: maintains nutritional status in patients with chronic gastrointestinal failure.

How It Works

  • The emulsion supplies long‑chain triglycerides that are hydrolyzed by lipases to free fatty acids, which are then incorporated into cell membranes and used as an energy substrate. The amino acids in the formulation support protein synthesis and nitrogen balance, while the lipid particles provide essential fatty acids required for eicosanoid synthesis and cellular signaling.

Side Effects

Nutriflex Lipid 32/64/40 Perifer may be associated with infusion‑related reactions and metabolic disturbances.

Common Side Effects

  • Hypertriglyceridaemia: elevated serum triglyceride levels during therapy.
  • Fever or chills: transient temperature rise during infusion.
  • Mild hepatic enzyme elevation: slight increase in ALT/AST.
  • Electrolyte shifts: changes in phosphate or magnesium levels.
  • Local vein irritation: discomfort at the infusion site.

Serious or Rare Side Effects

  • Anaphylactic reaction: acute hypersensitivity requiring immediate intervention.
  • Fat overload syndrome: excessive lipid accumulation leading to organ dysfunction.
  • Pulmonary embolism: lipid droplets entering the pulmonary circulation.
  • Severe hyperlipidaemia: marked rise in serum lipids with pancreatitis risk.
  • Coagulopathy: impaired clotting due to lipid‑induced platelet dysfunction.

Precautions & Warnings

When prescribing Nutriflex Lipid 32/64/40 Perifer, clinicians should assess metabolic status and monitor laboratory parameters.

  • Baseline lipid profile: obtain triglyceride and cholesterol levels before initiation.
  • Liver function monitoring: check ALT, AST, and bilirubin regularly.
  • Glycaemic control: observe blood glucose in diabetic patients.
  • Electrolyte balance: monitor phosphate, magnesium and calcium during therapy.
  • Infusion rate: administer according to recommended guidelines to reduce risk of fat overload.
  • Store at ambient temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Nutriflex Lipid 32/64/40 Perifer can interact with other intravenous therapies and metabolic modulators.

Major Interactions (Avoid)

  • Propofol: concurrent lipid infusion may cause cumulative fat load and hypertriglyceridaemia.
  • Heparin: may increase plasma lipase activity, enhancing triglyceride breakdown and risk of fat overload.
  • High‑dose vitamin A: excess fat‑soluble vitamins can accumulate in the lipid phase.

Moderate Interactions (Monitor Closely)

  • Insulin therapy: lipid infusion can affect glycaemic control, requiring dose adjustments.
  • Anticoagulants: lipid particles may alter plasma protein binding, affecting anticoagulant activity.
  • Other parenteral nutrition components: coordinate macronutrient ratios to avoid excess calories.

Frequently Asked Questions

Nutriflex Lipid 32/64/40 Perifer is an intravenous lipid emulsion used to provide essential fatty acids and calories for patients who cannot receive adequate nutrition by mouth or tube feeding, such as after surgery, during severe malnutrition, or in long‑term parenteral nutrition programs.

Valine, together with other amino acids in the formulation, supports protein synthesis and nitrogen balance, while the lipid component supplies long‑chain triglycerides that are hydrolysed to free fatty acids for energy production and cell‑membrane construction.

The prescribed dose is determined by the treating clinician based on the patient’s caloric needs, weight, and metabolic status. Dosing is individualized and administered under medical supervision.

Safety in pregnancy or lactation has not been established. The product should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and it must be prescribed by a qualified healthcare professional.

Enquiries can be submitted on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nutriflex Lipid 32/64/40 Perifer offers a specific fatty‑acid profile and includes a balanced amino‑acid mix, which may differ from other emulsions that contain alternative oil sources or varying concentrations of omega‑3 fatty acids. Choice of product depends on clinical goals, patient tolerance and institutional protocols.

The emulsion should be stored at ambient temperature, protected from light and moisture, and kept in its original container until use. Once opened, it must be used within the time frame specified by the manufacturer.

It is administered intravenously, typically via a central venous catheter, using an infusion pump to control the rate. Administration guidelines recommend gradual infusion to minimise the risk of fat overload and infusion‑related reactions.

Serious risks include anaphylactic reactions, fat overload syndrome, pulmonary embolism from lipid droplets, severe hyperlipidaemia and coagulopathy. Prompt recognition and management of these events are essential.

Patients with known hypersensitivity to any component of the emulsion, severe hypertriglyceridaemia, uncontrolled sepsis, or those at high risk for fat overload should not receive this product unless benefits clearly outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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