Nutriflex Lipid 56/144/40 (Valine, Alanine, Arginine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, Threonin)

Nutriflex Lipid 56/144/40 provides a complete lipid and amino‑acid profile for patients with increased metabolic demand. It is used in the following clinical situations:

• Critical care: Enhances nutritional support for critically ill patients receiving intensive therapy.
• Post‑operative recovery: Supports protein and energy needs during post‑surgical healing.
• Long‑term parenteral nutrition: Maintains nutrient balance when enteral feeding is not feasible.
• Severe malnutrition: Provides essential amino acids and lipids to reverse catabolic states in malnourished patients.

• The formulation supplies essential amino acids—including valine, leucine, isoleucine and others—directly into the bloodstream, bypassing gastrointestinal absorption. These amino acids act as substrates for protein synthesis, stimulate the mTOR pathway, and provide substrates for gluconeogenesis, while the lipid component supplies essential fatty acids for membrane integrity and energy production.

Nutriflex Lipid 56/144/40 may be associated with infusion‑related reactions and metabolic disturbances.

Common Side Effects

• Hyperglycaemia: Elevated blood glucose during infusion.
• Hypertriglyceridaemia: Increased serum triglyceride levels.
• Electrolyte imbalance: Shifts in potassium, phosphate or magnesium.
• Mild fever or chills: Transient temperature rise during administration.
• Local site irritation: Redness or discomfort at the infusion site.

Serious or Rare Side Effects

• Anaphylaxis: Acute, potentially life‑threatening allergic reaction.
• Hepatic dysfunction: Elevated liver enzymes indicating liver stress.
• Metabolic acidosis: Decrease in blood pH due to acid accumulation.
• Coagulopathy: Abnormal clotting parameters or bleeding tendency.

When using Nutriflex Lipid 56/144/40, clinicians should consider several safety measures.

• Monitor glucose: Check blood glucose regularly during infusion.
• Assess triglycerides: Measure serum triglyceride levels before and during therapy.
• Electrolyte surveillance: Observe potassium, phosphate and magnesium concentrations.
• Liver function tests: Perform baseline and periodic liver enzyme assessments.
• Infection control: Use aseptic technique to prevent catheter‑related infections.
• Store at ambient temperature: Keep below 25°C, in the original packaging, protected from moisture.

Nutriflex Lipid 56/144/40 can interact with other agents that influence metabolism or coagulation.

Major Interactions (Avoid)

• Propofol: Concurrent lipid infusion may cause severe hypertriglyceridaemia.
• High‑dose insulin insulin: May exacerbate hypoglycaemia when combined with the amino‑acid load.

Moderate Interactions (Monitor Closely)

• Heparin‑containing catheters: May increase risk of hypertriglyceridaemia.
• Loop diuretics: Can potentiate electrolyte disturbances, especially potassium loss.
• Corticosteroids: May augment hyperglycaemic response during infusion.