Nutriflex Omega 56/144 S (Valine, Alanine, Arginine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, Threonin)

Nutriflex Omega 56/144 S is used as part of parenteral nutrition regimens for patients who cannot meet protein and amino‑acid requirements orally.

• Critical illness: supports protein synthesis and nitrogen balance in intensive‑care patients.
• Post‑operative recovery: aids wound healing and tissue repair after major surgery.
• Severe malnutrition: supplies essential amino acids when oral intake is insufficient or contraindicated.

• The formulation delivers a balanced profile of essential and non‑essential amino acids directly into the bloodstream, bypassing gastrointestinal absorption. These amino acids serve as substrates for protein synthesis, support nitrogen balance, and act as precursors for neurotransmitters and metabolic intermediates, thereby sustaining cellular function during periods of catabolic stress.

Adverse reactions are generally related to the intravenous route and the amino‑acid composition.

Common Side Effects

• Mild infusion site erythema: localized redness at the catheter site.
• Transient nausea: brief episodes of nausea during or shortly after infusion.
• Hyperglycaemia: temporary rise in blood glucose levels, especially in diabetic patients.
• Electrolyte shifts: mild changes in serum potassium or phosphate.
• Headache: occasional mild headache during treatment.

Serious or Rare Side Effects

• Anaphylactic reaction: severe allergic response requiring immediate medical intervention.
• Severe hyperammonemia: marked increase in blood ammonia levels.
• Metabolic acidosis: significant drop in blood pH.
• Hepatic dysfunction: abnormal liver enzyme elevations.
• Renal impairment: worsening kidney function in susceptible individuals.

When prescribing Nutriflex Omega 56/144 S, clinicians should consider patient‑specific factors and monitor relevant parameters.

• Renal function: assess creatinine clearance before initiation and during therapy.
• Hepatic status: evaluate liver enzymes and function tests.
• Metabolic disorders: monitor glucose and electrolyte levels regularly.
• Allergic history: verify absence of known hypersensitivity to any amino‑acid component.
• Infusion rate: adhere to recommended infusion speeds to minimise phlebitis.
• Store at 2‑8°C: keep refrigerated, protect from light, do not freeze or shake.

Amino‑acid solutions may interact with certain medications or clinical conditions.

Major Interactions (Avoid)

• High‑dose potassium supplements: can exacerbate hyperkalaemia when combined.
• Certain antibiotics (e.g., aminoglycosides): may increase nephrotoxic risk.

Moderate Interactions (Monitor Closely)

• Insulin therapy: may require dose adjustment due to glucose fluctuations.
• Loop diuretics: monitor electrolyte balance, especially potassium and magnesium.
• Anticonvulsants (e.g., valproate): may alter plasma amino‑acid levels.
• Corticosteroids: can affect protein catabolism rates.
• Total parenteral nutrition admixtures: ensure compatibility before co‑administration.