Product image of Nutriflex Peri (Valine, Arginine Glutamate, Alanine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine) supplied by GNH India

Nutriflex Peri

Active Ingredient:
Valine, Arginine Glutamate, Alanine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine
Origin:
EU

Nutriflex Peri (Valine, Arginine Glutamate, Alanine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine)

Valine, Arginine Glutamate, Alanine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, the active ingredient in Nutriflex Peri, is a parenteral nutrition solution presented as a solution for injection for intravenous use. It provides essential amino acids to support protein synthesis and nitrogen balance in patients who require parenteral nutrition, such as those undergoing surgery or experiencing critical illness.

GNH India supplies Nutriflex Peri as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

B.Braun Melsungen Ag

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Indications & Clinical Uses

Nutriflex Peri is used in the context of parenteral nutrition to address protein and nitrogen needs in several clinical situations.

  • Perioperative nutrition support: supplies essential amino acids to maintain nitrogen balance during and after surgery.
  • Patients requiring parenteral nutrition: provides a complete amino acid profile when oral intake is insufficient.
  • Postoperative recovery: aids tissue repair and wound healing by delivering substrates for protein synthesis.
  • Critical illness nutrition: helps sustain metabolic demands in severely ill or ICU patients.

How It Works

  • The solution delivers a balanced mixture of essential and non‑essential amino acids directly into the bloodstream, bypassing the gastrointestinal tract. These amino acids become substrates for protein synthesis, support nitrogen balance, and contribute to the formation of enzymes, neurotransmitters, and immune mediators, thereby facilitating tissue repair and metabolic stability during intravenous nutrition.

Side Effects

Adverse reactions may occur with any parenteral infusion. Monitoring during administration is recommended.

Common Side Effects

  • Infusion site erythema or pain
  • Phlebitis or thrombophlebitis
  • Hypernatremia due to sodium content
  • Metabolic alkalosis from amino acid metabolism
  • Elevated serum urea nitrogen
  • Mild hyperglycemia in susceptible patients

Serious or Rare Side Effects

  • Anaphylactic or severe hypersensitivity reaction
  • Severe hyperammonemia leading to encephalopathy
  • Acute renal dysfunction or failure
  • Electrolyte disturbances causing cardiac arrhythmia
  • Severe metabolic acidosis or alkalosis requiring intervention

Precautions & Warnings

Careful assessment and monitoring are essential when using this parenteral amino acid solution.

  • Renal function assessment: evaluate creatinine clearance before initiation.
  • Electrolyte monitoring: check serum potassium, sodium, and calcium levels regularly.
  • Plasma amino acid levels: monitor to avoid excess nitrogen load.
  • Hypersensitivity screening: avoid in patients with known allergy to any amino acid component.
  • Aseptic technique: ensure sterile preparation and administration to prevent infection.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Amino acid solutions can interact with other intravenous therapies and metabolic conditions.

Major Interactions (Avoid)

  • Concurrent high‑dose amino acid solutions may cause nitrogen overload.
  • Co‑administration with potassium‑rich fluids can precipitate hyperkalemia.
  • Use with certain diuretics may exacerbate electrolyte imbalances.

Moderate Interactions (Monitor Closely)

  • Insulin therapy may alter glucose control when combined with amino acid infusion.
  • Nephrotoxic drugs require close renal monitoring during concurrent use.
  • Compatibility checks needed when mixing with other parenteral nutrition components to prevent precipitation.

Frequently Asked Questions

Nutriflex Peri is an intravenous amino acid solution used to provide essential proteins and maintain nitrogen balance in patients who cannot receive nutrition orally. It is indicated for perioperative nutrition support, postoperative recovery, critical illness, and any clinical situation where parenteral nutrition is required.

The blend supplies a complete profile of essential and non‑essential amino acids directly into the bloodstream. These amino acids serve as building blocks for protein synthesis, support metabolic pathways, and help maintain nitrogen equilibrium, which is crucial for tissue repair, immune function, and overall metabolic stability during intravenous feeding.

The dose of Nutriflex Peri is individualized and determined by the prescribing clinician based on the patient’s weight, metabolic needs, renal function, and overall clinical condition. The healthcare professional calculates the appropriate volume and rate of infusion to meet the patient’s nutritional requirements.

The safety of Nutriflex Peri in pregnancy or lactation has not been definitively established. Use should be considered only if the potential benefit justifies any potential risk to the mother or infant, and the decision must be made by the treating physician in consultation with obstetric specialists.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics if needed), and the necessary import documentation.

Nutriflex Peri offers a comprehensive amino acid profile that matches the WHO/FAO recommended pattern for adult nutrition, making it comparable to other high‑quality amino acid solutions. Its EU‑origin manufacturing ensures compliance with stringent quality standards, and its formulation is designed for compatibility with standard parenteral nutrition regimens.

Nutriflex Peri must be stored refrigerated at 2‑8 °C. Keep the container in its original packaging, protect it from light, and avoid freezing or shaking the solution. Before use, inspect the vial for any particulate matter or discoloration and discard if any abnormalities are observed.

The product is supplied as a sterile solution for injection and is administered intravenously. It is typically infused through a dedicated line or a compatible infusion set, following aseptic technique. The infusion rate is set according to the prescribing clinician’s orders and the patient’s tolerance.

Serious risks include severe hypersensitivity reactions such as anaphylaxis, hyperammonemia leading to neurological symptoms, and acute renal dysfunction due to nitrogen overload. Prompt recognition and immediate medical intervention are essential if any of these events occur during or after infusion.

Nutriflex Peri should be avoided in patients with a documented hypersensitivity to any of its amino acid components, in those with uncontrolled hyperkalemia or severe electrolyte disturbances, and in individuals with severe renal impairment where nitrogen clearance is compromised, unless a specialist determines that benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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