Nutriflex Plus N (Valine, Arginine Glutamate, Alanine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine)

Nutriflex Plus N provides a balanced mixture of essential and non‑essential amino acids for patients with increased protein turnover. It is used in clinical situations where amino acid supplementation supports recovery and metabolic stability.

• Critical illness: helps maintain nitrogen balance and supports tissue repair.
• Post‑operative care: contributes to wound healing and muscle preservation.
• Severe malnutrition: provides essential amino acids to improve nutritional status.
• Burn injuries: aids in protein synthesis and reduces catabolism.
• Long‑term parenteral nutrition: serves as a component of total nutrient admixtures.
• Hepatic encephalopathy: assists in reducing ammonia‑related toxicity.

• Nutriflex Plus N delivers a defined profile of essential and non‑essential amino acids directly into the bloodstream, bypassing gastrointestinal absorption. The amino acids serve as substrates for protein synthesis, support gluconeogenesis, and participate in neurotransmitter and nitric oxide production, thereby helping to restore nitrogen balance and support cellular metabolism in critically ill or malnourished patients.

Nutriflex Plus N may elicit a range of adverse reactions, most of which are related to its intravenous administration and amino‑acid composition.

Common Side Effects

• Mild infusion‑related erythema
• Transient increase of serum potassium or magnesium
• Slight headache or dizziness
• Nausea or vomiting
• Low blood pressure (hypotension)
• Mild metabolic alkalosis 

Serious or Rare Side Effects

• Severe hypersensitivity or anaphylaxis 
• Acute renal injury 
• Hyperosmolar hyper‑glycerol syndrome 
• Metabolic acidosis 
• Electrolyte disturbances requiring intervention
• Thrombophlebitis at the infusion site.

Nutriflex Plus N should be administered under clinical supervision with attention to patient‑specific factors.

• Renal function: assess baseline creatinine and monitor during therapy.
• Hepatic function: evaluate liver enzymes before initiation.
• Electrolyte balance: check serum electrolytes and adjust as needed.
• Infusion rate: follow recommended guidelines to minimise phlebitis risk.
• Compatibility: verify compatibility with other intravenous solutions before mixing.
• Store at ambient temperature: keep in original container, protect from moisture and direct sunlight.

Nutriflex Plus N may interact with other intravenous agents, influencing electrolyte and osmolar balance.

Major Interactions (Avoid)

• High‑dose potassium chloride solutions: may cause severe hyperkalaemia.
• Hypertonic glucose solutions: increase risk of hyperosmolar complications.
• Certain antibiotics antibiotics ;  

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