Product image of Nutrineal Pd4 (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin) supplied by GNH India

Nutrineal Pd4

Active Ingredient:
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Origin:
EU

Nutrineal Pd4 (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin)

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Nutrineal Pd4, is a nutrition supplement presented as a sterile solution for intraperitoneal use. It supports nutritional status in patients requiring intraperitoneal nutrition.

GNH India supplies Nutrineal Pd4 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Vantive Belgium

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Indications & Clinical Uses

Nutrineal Pd4 is used to support nutritional status via intraperitoneal amino‑acid delivery in patients requiring parenteral nutrition.

  • Patients receiving intraperitoneal nutrition: improves protein synthesis and metabolic support.
  • Critically ill patients: helps maintain nitrogen balance and muscle mass.
  • Post‑surgical patients: aids wound healing and recovery.

How It Works

  • Nutrineal Pd4 provides a balanced mixture of essential amino acids that serve as substrates for protein synthesis, replenish nitrogen stores, and stimulate hepatic albumin production. The amino acids are absorbed directly into the peritoneal cavity, entering the systemic circulation to support cellular metabolism, tissue repair, and overall nutritional homeostasis.

Side Effects

Adverse reactions may occur with any parenteral nutrition product and should be monitored.

Common Side Effects

  • Local irritation at the injection site: mild pain or redness.
  • Transient hyperammonemia: temporary rise in blood ammonia levels.
  • Mild nausea: occasional gastrointestinal discomfort.
  • Electrolyte shift: minor changes in serum potassium or phosphate.
  • Fever: low‑grade temperature elevation.
  • Headache: occasional mild headache.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergy requiring immediate medical attention.
  • Metabolic acidosis: significant pH imbalance.
  • Severe hyperglycemia: marked increase in blood glucose.
  • Hepatic dysfunction: rare liver enzyme elevation.
  • Thrombophlebitis: inflammation of veins used for infusion.
  • Sepsis: systemic infection linked to catheter use.

Precautions & Warnings

When using Nutrineal Pd4, clinicians should consider several safety measures.

  • Renal function assessment: evaluate creatinine clearance before initiation.
  • Liver monitoring: check transaminases and bilirubin regularly.
  • Amino‑acid balance: avoid excessive cumulative dosing.
  • Hypersensitivity screening: discontinue if allergic signs appear.
  • Adjust in hepatic impairment: reduce infusion rate as needed.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Nutrineal Pd4 may interact with other therapies that affect nitrogen balance or metabolic pathways.

Major Interactions (Avoid)

  • Concurrent high‑dose amino‑acid solutions: risk of excess nitrogen load.
  • Renal replacement therapy: altered clearance may require dose adjustment.

Moderate Interactions (Monitor Closely)

  • Insulin therapy: may affect glucose control.
  • Corticosteroids: increase protein catabolism.
  • Electrolyte supplements: monitor potassium and phosphate levels.
  • Diuretics: potential electrolyte disturbances.
  • Anticoagulants: observe for catheter‑related bleeding.

Frequently Asked Questions

Nutrineal Pd4 is a parenteral nutrition supplement that provides essential amino acids via the intraperitoneal route. It is used to support the nutritional status of patients who cannot receive oral or enteral feeding, such as those undergoing major surgery, critical illness, or with gastrointestinal failure.

The blend supplies the building blocks required for protein synthesis, replenishes nitrogen stores, and stimulates hepatic albumin production. By delivering these amino acids directly into the peritoneal cavity, they are absorbed into the bloodstream, supporting cellular metabolism, tissue repair, and overall nutritional balance.

The dose of Nutrineal Pd4 is individualized. A qualified prescriber determines the appropriate volume and infusion rate based on the patient’s weight, clinical condition, renal and hepatic function, and overall nutritional requirements.

Safety data for Nutrineal Pd4 in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and under close medical supervision.

To order Nutrineal Pd4, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Nutrineal Pd4 offers a comprehensive essential amino‑acid profile specifically formulated for intraperitoneal delivery, whereas many alternatives are designed for intravenous use. Its amino‑acid composition aims to match physiological requirements, potentially providing more efficient protein synthesis for patients receiving intraperitoneal nutrition.

Nutrineal Pd4 should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the product from moisture, direct sunlight, and extreme temperatures to maintain sterility and stability.

The product is administered as a sterile solution via an intraperitoneal catheter. The infusion rate and total volume are set by the prescribing clinician, and the administration is typically performed in a controlled clinical setting with aseptic technique.

Serious risks include anaphylactic reactions, metabolic acidosis, severe hyperglycemia, hepatic dysfunction, and catheter‑related infections such as sepsis. Patients should be monitored closely for signs of these events, and treatment should be stopped immediately if they occur.

Patients with known hypersensitivity to any of the amino‑acid components, those with uncontrolled metabolic disorders, severe hepatic or renal failure without dose adjustment, and individuals with active infections at the catheter site should avoid using Nutrineal Pd4.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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