Product image of Nutrineal Pd4 (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin) supplied by GNH India

Nutrineal Pd4

Active Ingredient:
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Origin:
EU

Nutrineal Pd4 (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin)

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin, the active ingredient in Nutrineal Pd4, is a amino acid solution presented as a solution for injection for intraperitoneal use. It provides essential amino acids for patients requiring parenteral nutrition who cannot receive enteral feeding.

GNH India supplies Nutrineal Pd4 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and clinics worldwide.

Manufacturer / TM Owner

Vantive S.R.L.

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Indications & Clinical Uses

  • Nutrineal Pd4 is used in parenteral nutrition to support patients who cannot receive enteral feeding.
  • Parenteral nutrition: supplies essential amino acids to maintain nitrogen balance in patients receiving total parenteral nutrition.
  • Critical care: supports protein synthesis in critically ill patients unable to eat orally or via tube.
  • Surgical recovery: provides amino acid supplementation during postoperative periods when enteral intake is delayed.

How It Works

  • Nutrineal Pd4 delivers a balanced mixture of essential amino acids that serve as substrates for protein synthesis, helping to maintain nitrogen balance, support tissue repair, and sustain metabolic functions in patients who are unable to obtain nutrition through the gastrointestinal tract.

Side Effects

Common Side Effects

  • Hyperglycemia: elevated blood glucose levels may occur.
  • Electrolyte imbalance: shifts in potassium, sodium, or calcium.
  • Local irritation: redness or discomfort at the injection site.
  • Fluid overload: excess volume may affect cardiac function.

Serious or Rare Side Effects

  • Metabolic acidosis: significant pH reduction in blood.
  • Allergic reaction (anaphylaxis): severe hypersensitivity requiring immediate treatment.
  • Renal dysfunction: impaired kidney function in susceptible patients.

Precautions & Warnings

Nutrineal Pd4 requires careful clinical monitoring and individualized use.

  • Dose adjustment: tailor dosage based on renal and hepatic function.
  • Monitoring: regularly assess plasma amino acid levels and electrolytes.
  • Fluid balance: watch for overload in patients with cardiac failure.
  • Compatibility: verify compatibility with other IV solutions before mixing.
  • Pregnancy and lactation: use only if benefit outweighs risk, as data are limited.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Nutrineal Pd4 may interact with other therapies that affect nitrogen balance or electrolyte status.

Major Interactions (Avoid)

  • Concurrent high‑dose amino acid solutions: risk of excess nitrogen load.
  • Renal replacement therapy: may alter clearance of amino acids.

Moderate Interactions (Monitor Closely)

  • Insulin therapy: amino acids may affect glucose control.
  • Electrolyte‑containing IV fluids: monitor for additive electrolyte shifts.
  • Diuretics: may increase risk of electrolyte imbalance.

Frequently Asked Questions

Nutrineal Pd4 is a sterile amino acid solution used as a component of total parenteral nutrition. It supplies essential amino acids to patients who cannot receive nutrition through the gastrointestinal tract, such as those in intensive care, after major surgery, or with severe gastrointestinal disorders.

The blend provides the nine essential amino acids that the body cannot synthesize. These amino acids become building blocks for protein synthesis, help maintain nitrogen balance, support tissue repair, and contribute to metabolic processes when delivered directly into the bloodstream.

The prescribed dose of Nutrineal Pd4 is individualized by the treating physician based on the patient’s weight, clinical condition, renal and hepatic function, and overall nutritional goals. No fixed regimen is provided; dosing is determined by the healthcare professional.

Safety data for Nutrineal Pd4 in pregnancy and lactation are limited. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the prescribing clinician.

To order Nutrineal Pd4, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain where required) and necessary import documentation.

Nutrineal Pd4 offers a comprehensive profile of essential amino acids in a single sterile solution, matching the composition of many standard TPN amino acid formulations. Compared with multi‑component kits, it simplifies preparation but should still be evaluated for compatibility with other IV admixtures used in a specific clinical protocol.

Nutrineal Pd4 must be stored refrigerated at 2‑8 °C. Keep the vial in its original packaging, protect it from light, and avoid freezing or shaking the solution. Inspect the product before use for any particulate matter or discoloration.

Nutrineal Pd4 is administered as a sterile solution for injection. It is typically infused intraperitoneally or intravenously using aseptic technique, under the supervision of qualified healthcare personnel, and the infusion rate is set according to the patient’s nutritional plan.

The most serious risks include metabolic acidosis, severe allergic reactions such as anaphylaxis, and renal dysfunction, especially in patients with pre‑existing kidney disease. Prompt recognition and appropriate medical intervention are essential if any of these events occur.

Nutrineal Pd4 should be avoided in patients with known hypersensitivity to any of its amino acid components, in those with severe uncontrolled renal failure, or in individuals where the risk of fluid overload outweighs the nutritional benefit. Clinical judgment is required for all contraindications.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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