Product image of Nytol Herbal Simply Sleep One-A-Night (Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V) supplied by GNH India

Nytol Herbal Simply Sleep One-A-Night

Active Ingredient:
Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V
Origin:
EU

Nytol Herbal Simply Sleep One-A-Night (Dry Extract Of Valerian Root, Extraction Solvent: Ethanol 60% V/V)

Valerian root extract, the active ingredient in Nytol Herbal Simply Sleep One-A-Night, is a herbal supplement presented as an oral tablet for nightly use. It is intended to help adults who experience occasional difficulty falling or staying asleep.

GNH India supplies Nytol Herbal Simply Sleep One-A-Night as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

G R Lane Health Products Ltd.

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Indications & Clinical Uses

Valerian root extract acts on the central nervous system to promote relaxation and support normal sleep patterns.

  • Mild insomnia: helps reduce the time needed to fall asleep.
  • Sleep maintenance difficulty: may improve continuity of sleep throughout the night.
  • Restless sleep: may promote deeper, less fragmented sleep.

How It Works

  • Valerian root extract contains valerenic acids, iridoids and volatile oils that modulate the GABA‑A receptor complex, enhancing inhibitory neurotransmission. It also influences serotonergic and glutamatergic pathways, leading to reduced neuronal excitability and a calming effect that facilitates the onset of sleep without directly binding to benzodiazepine sites.

Side Effects

Adverse reactions reported with valerian root extract are generally mild and reversible.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Dizziness: transient sensation of light‑headedness.
  • Gastrointestinal upset: nausea or stomach discomfort.
  • Dry mouth: reduced salivation.
  • Fatigue: feeling of tiredness during the day.
  • Vivid dreams: unusually intense dreaming.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, or swelling.
  • Liver enzyme elevation: abnormal liver function tests.
  • Severe skin rash: Stevens‑Johnson‑like presentation.
  • Hallucinations: rare perceptual disturbances.
  • Anaphylaxis: rapid onset of airway compromise (extremely rare).

Precautions & Warnings

Valerian root extract should be used with awareness of specific safety considerations.

  • Pregnancy: avoid unless advised by a healthcare professional.
  • Breastfeeding: caution, as limited data are available.
  • Concurrent CNS depressants: monitor for additive sedation.
  • Alcohol consumption: avoid to reduce excessive drowsiness.
  • Liver disease: use with caution and monitor liver function.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Valerian root extract may interact with other substances that affect the central nervous system.

Major Interactions (Avoid)

  • Benzodiazepines: additive CNS depression.
  • Barbiturates: increased sedative effect.
  • Alcohol: excessive drowsiness and impaired coordination.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs): possible enhanced sedation.
  • Antihistamines: additive drowsiness.
  • Opioids: increased risk of respiratory depression.

Frequently Asked Questions

Nytol Herbal Simply Sleep One-A-Night is a herbal supplement containing valerian root extract. It is used to support occasional difficulty falling asleep or staying asleep, helping adults achieve a more natural sleep pattern without prescription medication.

Valerian root extract contains compounds such as valerenic acids that enhance the activity of the GABA‑A receptor, the main inhibitory neurotransmitter system in the brain. This modulation reduces neuronal excitability, producing a calming effect that can shorten the time needed to fall asleep and improve sleep continuity.

The appropriate dose of Nytol Herbal Simply Sleep One-A-Night is determined by the prescribing healthcare professional based on individual needs, age, and health status. Patients should follow the specific instructions provided by their clinician or pharmacist.

Safety data for valerian root extract in pregnancy and lactation are limited. It is generally recommended that pregnant or breastfeeding women avoid using this product unless a qualified healthcare provider determines that the potential benefits outweigh any possible risks.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Unlike synthetic hypnotics such as zolpidem, Nytol Herbal Simply Sleep One-A-Night relies on a natural herbal extract (valerian) that modulates GABA activity without binding to benzodiazepine receptors. It is generally considered milder, with a lower risk of dependence, but may be less potent for severe insomnia.

Store the tablets at ambient temperature, preferably below 25 °C, in the original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

The product is taken orally, typically with a glass of water, shortly before bedtime. Users should avoid taking it with alcohol or other central nervous system depressants to reduce the risk of excessive sedation.

Serious but rare risks include allergic reactions such as rash, swelling, or anaphylaxis, and potential liver enzyme elevations. Any signs of severe skin reaction, breathing difficulty, or unusual liver-related symptoms should prompt immediate medical attention.

Individuals with known hypersensitivity to valerian or any excipients, those taking strong CNS depressants, patients with severe liver disease, pregnant or breastfeeding women (unless advised by a clinician), and children should avoid using this product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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