Product image of Nyxoid (Naloxone) supplied by GNH India

Nyxoid

Active Ingredient:
Naloxone
Origin:
EU

Nyxoid (Naloxone)

Naloxone, the active ingredient in Nyxoid, is an opioid antagonist presented as a 0.4 mg/mL solution for intramuscular injection use. It rapidly reverses opioid overdose in emergency situations, restoring normal breathing in affected individuals. GNH India supplies Nyxoid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

GNH India supplies Nyxoid as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mundipharma Corporation (Ireland) Limited

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Indications & Clinical Uses

Naloxone is an opioid antagonist used in the management of opioid‑related emergencies.

  • Opioid overdose: quickly restores respiration and consciousness in patients experiencing life‑threatening respiratory depression.
  • Post‑operative pain management: reverses unintended opioid effects after surgery.
  • Diagnostic challenge: helps differentiate opioid‑induced sedation from other causes of altered mental status.
  • Opioid dependence treatment: used in supervised settings to precipitate withdrawal and assess tolerance.
  • Emergency medical services: part of standard protocols for first‑responder kits.
  • Community overdose response: stocked in public spaces for layperson use.

How It Works

  • Naloxone is a competitive antagonist at the μ‑opioid receptor. By binding to these receptors without activating them, it displaces opioid agonists such as morphine, heroin, and fentanyl, rapidly reversing their central nervous system effects and restoring normal respiratory drive and consciousness.

Side Effects

Naloxone is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea
  • Vomiting
  • Sweating
  • Tremor
  • Flushing
  • Headache

Serious or Rare Side Effects

  • Acute hypertension
  • Cardiac arrhythmias
  • Seizures
  • Pulmonary edema.

Precautions & Warnings

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Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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