O-Biotic (Dexamethasone, Tobramycin)

Dexamethasone is a synthetic glucocorticoid that binds to intracellular glucocorticoid receptors. This interaction modulates gene expression, suppressing the release of inflammatory mediators, reducing edema, and inhibiting leukocyte migration, thereby decreasing ocular inflammation.

The dosage of O-Biotic is determined by the prescribing clinician based on the specific condition, severity, and patient factors. The prescriber will specify the number of drops, frequency, and duration appropriate for each case.

Pregnancy and breastfeeding considerations should be discussed with a healthcare professional. Dexamethasone is classified as pregnancy category C, and both ingredients may be excreted in breast milk, so caution is advised and benefits must outweigh potential risks.

To order O-Biotic, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

O-Biotic combines a corticosteroid (dexamethasone) with an aminoglycoside antibiotic (tobramycin), offering both anti‑inflammatory and antibacterial activity in a single formulation. In contrast, many eye antibiotics lack anti‑inflammatory properties, requiring separate steroid therapy for inflammation.

O-Biotic should be stored below 25 °C, in its original container, protected from moisture and direct sunlight. Keep the suspension tightly sealed and avoid freezing. Follow any additional handling instructions provided on the label.

O-Biotic is applied as an ophthalmic suspension. The prescribed number of drops is instilled into the affected eye(s) at the frequency indicated by the prescriber, typically using a sterile dropper to avoid contamination.

Serious risks include allergic reactions such as eyelid swelling or rash, secondary ocular infections, corneal ulceration, increased intra‑ocular pressure leading to glaucoma, and cataract formation with prolonged use. Patients should be monitored for these events.

O-Biotic should be avoided in patients with known hypersensitivity to dexamethasone, tobramycin, or any formulation components. It is also contraindicated in viral eye infections (e.g., herpes simplex keratitis) and in individuals for whom corticosteroid use is prohibited.