Product image of Octanine (Human Coagulation Factor Ix) supplied by GNH India

Octanine

Active Ingredient:
Human Coagulation Factor Ix
Origin:
EU

Octanine (Human Coagulation Factor Ix)

Human Coagulation Factor IX, the active ingredient in Octanine, is a coagulation factor replacement therapy presented as an intravenous solution for intravenous use. It replaces deficient factor IX in patients with hemophilia B, helping to control bleeding episodes. GNH India supplies Octanine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

GNH India supplies Octanine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

Octapharma As

1
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Indications & Clinical Uses

Octanine is a recombinant factor IX product that operates within the intrinsic pathway of the clotting cascade for hemophilia B management as follows:

  • Hemophilia B: Provides temporary replacement of factor IX to reduce bleeding frequency and severity during bleeds or surgery .
  • Peri‑operative management of hemophilia B: Ensures adequate factor IX levels to maintain hemostasis during surgical procedures.
  • Prophylaxis of hemophilia B: Regular administration to maintain baseline factor IX levels and prevent spont sp sp sp sp sp.

How It Works

  • Octanine supplies an exogenous source of functional human coagulation factor IX, a vitamin‑dependent serine protease that participates in the intrinsic coagulation cascade. After intravenous infusion, the protein binds to activated factor VIII on phospholipid surfaces, catalyzing the conversion of factor X to Xa, which ultimately generates thrombin and forms a stable fibrin clot.

Side Effects

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Precautions & Warnings

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Avoid Interactions

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Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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