Product image of Ocuflox (Ofloxacin) supplied by GNH India

Ocuflox

Active Ingredient:
Ofloxacin
Origin:
EU

Ocuflox (Ofloxacin)

Ofloxacin, the active ingredient in Ocuflox, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It treats bacterial infections of the eye such as conjunctivitis and keratitis in patients requiring prescription therapy.

GNH India supplies Ocuflox as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Omnivision Italia S.R.L.

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Indications & Clinical Uses

Ofloxacin (Ocuflox) is used to treat bacterial infections of the eye, targeting the ocular surface and cornea.

  • Bacterial conjunctivitis: reduces bacterial load and resolves infection.
  • Bacterial keratitis: treats corneal infection and promotes healing.

How It Works

  • Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to these enzymes, it prevents bacterial DNA supercoiling, leading to inhibition of bacterial cell division and ultimately bacterial death. This bactericidal activity is effective against a broad spectrum of Gram‑negative and Gram‑positive ocular pathogens.

Side Effects

Common Side Effects

  • Eye irritation or burning sensation.
  • Redness of the conjunctiva.
  • Tearing or increased lacrimation.
  • Foreign body sensation.
  • Blurred vision.
  • Mild eyelid edema.

Serious or Rare Side Effects

  • Allergic reactions such as swelling, rash, or hives.
  • Corneal ulceration or severe eye pain.
  • Vision loss or sudden decrease in visual acuity.
  • Hypersensitivity leading to Stevens‑Johnson syndrome.
  • Persistent ocular inflammation.
  • Severe photophobia.

Precautions & Warnings

Before using Ocuflox, consider the following precautions:

  • Hypersensitivity: avoid if the patient has known allergy to fluoroquinolones.
  • Corneal epithelial defects: do not use on damaged corneal surfaces without medical advice.
  • Monitor for signs of allergic reaction during treatment.
  • Use with caution in patients with a history of tendon disorders due to possible systemic absorption.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

When co‑administering Ocuflox, be aware of potential drug interactions:

Major Interactions (Avoid)

  • Concurrent topical ophthalmic corticosteroids: may increase risk of secondary infection.
  • Systemic fluoroquinolones: additive systemic exposure may raise toxicity risk.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory eye drops: could affect wound healing.
  • Contact lens wear: may alter drug absorption and increase irritation.
  • Other ocular antibiotics: potential antagonistic effects on bacterial flora.

Frequently Asked Questions

Ocuflox is a prescription ophthalmic solution containing ofloxacin. It is used to treat bacterial infections of the eye, specifically bacterial conjunctivitis and bacterial keratitis, by eliminating the causative microorganisms.

Ofloxacin works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication. This interference prevents bacterial cell division, leading to bacterial death and resolution of the ocular infection.

The dosing regimen for Ocuflox is determined by the prescribing eye care professional based on the severity of the infection, patient age, and clinical response. Patients should follow the specific instructions provided by their healthcare provider.

Safety data for ofloxacin ophthalmic use in pregnancy or lactation are limited. The prescriber should weigh potential benefits against risks and consider alternative treatments if there are concerns about fetal or infant exposure.

To order Ocuflox, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Ocuflox (ofloxacin) belongs to the fluoroquinolone class, offering broad‑spectrum coverage against Gram‑negative and Gram‑positive bacteria. Compared with older agents like chloramphenicol, fluoroquinolones generally have higher potency and lower resistance rates, but selection should be guided by local antibiograms and patient tolerance.

Ocuflox should be stored at room temperature, below 25 °C, in its original packaging. Keep the bottle tightly closed, protect it from light, and avoid exposure to moisture to maintain stability and efficacy.

Ocuflox is applied topically to the affected eye(s) as directed by the prescriber, typically using a dropper to place the recommended number of drops at specified intervals. Patients should wash their hands before and after administration and avoid touching the dropper tip to the eye or any surface.

Serious risks include severe allergic reactions, corneal ulceration, vision loss, and rare systemic hypersensitivity such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience intense eye pain, worsening redness, swelling, or any signs of an allergic response.

Ocuflox should not be used by individuals with a known hypersensitivity to ofloxacin, other fluoroquinolones, or any component of the formulation. It is also contraindicated in patients with active corneal epithelial defects unless specifically directed by an eye care professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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