Product image of Oczyesa (Octreotide) supplied by GNH India

Oczyesa

Active Ingredient:
Octreotide
Origin:
EU

Oczyesa (Octreotide)

Octreotide, the active ingredient in Oczyesa, is a synthetic somatostatin analog presented as an injectable solution for subcutaneous or intravenous use. It regulates hormone secretion and reduces splanchnic blood flow, making it useful in adults with specific endocrine and gastrointestinal disorders.

GNH India supplies Oczyesa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Camurus Ab

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Octreotide acts on somatostatin receptors to control hormone‑driven conditions and bleeding disorders.

  • Acromegaly: reduces excessive growth hormone secretion and lowers serum IGF‑1 levels.
  • Carcinoid syndrome: diminishes flushing and diarrhea by inhibiting serotonin release.
  • VIPoma (vasoactive intestinal peptide tumor): controls severe watery diarrhea and electrolyte loss.
  • Bleeding from esophageal varices: decreases portal venous pressure and limits acute hemorrhage.

How It Works

  • Octreotide binds with high affinity to somatostatin receptor subtypes 2 and 5 on target cells, inhibiting adenylate cyclase activity and calcium influx. This suppresses the release of growth hormone, insulin, glucagon, gastrin, and vasoactive intestinal peptide, while also reducing splanchnic blood flow, leading to its therapeutic effects in hormone‑dependent tumors and portal hypertension.

Side Effects

Octreotide may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate gastrointestinal upset.
  • Abdominal pain: cramping or discomfort after injection.
  • Diarrhea: loose stools, often transient.
  • Injection site reactions: redness, swelling, or bruising.
  • Hyperglycemia: elevated blood glucose levels.
  • Gallstones: formation of biliary sludge or stones.

Serious or Rare Side Effects

  • Pancreatitis: severe abdominal pain with elevated enzymes.
  • Severe hypoglycemia: dangerously low blood glucose.
  • Cardiac arrhythmias: irregular heart rhythms.
  • Anaphylaxis: life‑threatening allergic reaction.
  • Hepatic dysfunction: abnormal liver function tests.
  • Severe gallbladder disease: cholecystitis or biliary colic.

Precautions & Warnings

Octreotide requires careful monitoring and patient education before use.

  • Glucose monitoring: assess blood sugar regularly, especially in diabetics.
  • Gallbladder assessment: perform ultrasound if symptomatic to detect stones.
  • Cardiac evaluation: monitor ECG in patients with known heart disease.
  • Renal/hepatic impairment: adjust dosing or monitor closely in dysfunction.
  • Hypersensitivity: avoid if known allergy to octreotide or formulation components.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Octreotide can alter the pharmacokinetics of several medicines.

Major Interactions (Avoid)

  • Cyclosporine: increased cyclosporine levels may cause nephrotoxicity.
  • Quinidine: octreotide can raise quinidine concentrations, risking arrhythmias.
  • Insulin: may mask hypoglycemia symptoms, requiring dose adjustment.

Moderate Interactions (Monitor Closely)

  • Oral contraceptives: reduced efficacy, consider alternative contraception.
  • Antidiabetic agents: may require dose changes due to altered glucose control.
  • Digoxin: possible changes in serum levels, monitor therapeutic range.

Frequently Asked Questions

Oczyesa contains octreotide, which is prescribed for adults with acromegaly, carcinoid syndrome, vasoactive intestinal peptide tumors, and for controlling acute bleeding from esophageal varices. The drug works by inhibiting hormone release and reducing blood flow in affected areas.

Octreotide mimics the natural hormone somatostatin and binds to somatostatin receptors, especially subtypes 2 and 5. This binding blocks the release of several hormones such as growth hormone, insulin, glucagon, and serotonin, and also reduces splanchnic blood flow, which underlies its therapeutic effects.

The specific dose and dosing schedule of Oczyesa are determined by the prescribing clinician based on the patient’s condition, severity, and response to therapy. Healthcare professionals tailor the regimen to achieve optimal clinical outcomes while minimizing adverse effects.

Octreotide should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is excreted in breast milk, so breastfeeding is generally not recommended while receiving treatment unless the benefits outweigh the risks. Consultation with a healthcare provider is essential.

To request Oczyesa, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Oczyesa (octreotide) is a short‑acting somatostatin analog, whereas some alternatives like lanreotide or long‑acting octreotide formulations provide extended dosing intervals. Choice depends on clinical needs, dosing convenience, and physician preference, with efficacy generally comparable across agents for approved indications.

Oczyesa should be stored at ambient temperature, below 25 °C, in its original packaging to protect from moisture and light. Do not freeze the product. Before administration, inspect the solution for particulate matter or discoloration and use aseptic technique.

Oczyesa is supplied as an injectable solution for subcutaneous or intravenous injection. The route, injection site, and frequency are determined by the prescribing clinician. Proper aseptic technique and correct needle size are essential for safe administration.

Serious risks include pancreatitis, severe hypoglycemia, cardiac arrhythmias, anaphylactic reactions, and significant gallbladder disease. Patients should be monitored for abdominal pain, sudden changes in blood glucose, heart rhythm disturbances, or signs of allergic reaction, and seek immediate medical attention if they occur.

Oczyesa is contraindicated in patients with known hypersensitivity to octreotide or any component of the formulation. Caution is advised for individuals with severe cardiac disease, uncontrolled diabetes, or active gallbladder disease. The prescriber should evaluate each patient’s medical history before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.