Product image of Ofloxa-Vision Sine (Ofloxacin) supplied by GNH India

Ofloxa-Vision Sine

Active Ingredient:
Ofloxacin
Origin:
EU

Ofloxa-Vision Sine (Ofloxacin)

Ofloxacin, the active ingredient in Ofloxa-Vision Sine, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It treats bacterial conjunctivitis, keratitis and other bacterial eye infections in both adults and children as prescribed. The sterile solution is formulated for topical instillation, delivering high local drug concentrations with minimal systemic absorption.

GNH India supplies Ofloxa-Vision Sine as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, transplant centres and ophthalmology clinics worldwide, adhering to EU quality standards and providing reliable global logistics.

Manufacturer / TM Owner

Omnivision Gmbh

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Indications & Clinical Uses

Ofloxa-Vision Sine, a fluoroquinolone antibiotic, is indicated for bacterial infections of the eye.

  • Bacterial conjunctivitis: reduces bacterial load and accelerates resolution of redness, discharge and irritation.
  • Bacterial keratitis: eradicates causative organisms and promotes corneal healing.
  • Other ocular bacterial infections: treats bacterial blepharitis and postoperative eye infections.

How It Works

  • Ofloxacin exerts its antibacterial effect by binding to the bacterial enzymes DNA gyrase (topoisomerase II) and topoisomerase IV. Inhibition of these enzymes prevents supercoiling and separation of bacterial DNA during replication and transcription, leading to bactericidal activity against a broad spectrum of Gram‑negative and Gram‑positive ocular pathogens. The high ocular tissue penetration achieved after topical administration ensures effective concentrations at the corneal epithelium and conjunctival sac.

Side Effects

Topical ocular administration of Ofloxa-Vision Sine may be associated with local and systemic adverse reactions.

Common Side Effects

  • Eye irritation or burning: transient discomfort upon instillation.
  • Redness: mild conjunctival hyperemia.
  • Blurred vision: temporary visual disturbance.

Serious or Rare Side Effects

  • Corneal ulceration: worsening corneal lesions.
  • Severe allergic reaction: swelling, itching, rash.
  • Anaphylaxis: systemic hypersensitivity requiring emergency care.

Precautions & Warnings

Before using Ofloxa-Vision Sine, consider the following precautions.

  • Avoid use in patients with known hypersensitivity to fluoroquinolones: discontinue immediately if a reaction occurs.
  • Do not wear contact lenses immediately after instillation: wait at least 15 minutes.
  • Monitor for signs of secondary infection: report persistent redness or discharge.
  • Limit duration of therapy to the prescribed period: avoid unnecessary prolonged use.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Ofloxa-Vision Sine may interact with other medicines; review the following.

Major Interactions (Avoid)

  • Concurrent use of topical ophthalmic corticosteroids: may reduce antibacterial efficacy.
  • Systemic fluoroquinolones: increased risk of additive toxicity.

Moderate Interactions (Monitor Closely)

  • Anticholinergic eye drops: may affect pupil size.
  • Other ocular antibiotics: potential antagonism.
  • Herbal supplements containing quinine: may potentiate systemic effects.

Frequently Asked Questions

Ofloxa-Vision Sine is a prescription ophthalmic solution containing ofloxacin. It is used to treat bacterial infections of the eye, including bacterial conjunctivitis, bacterial keratitis, and other ocular bacterial conditions such as blepharitis or postoperative infections, as determined by a qualified eye‑care professional.

Ofloxacin belongs to the fluoroquinolone class and works by inhibiting bacterial DNA gyrase and topoisomerase IV. These enzymes are essential for DNA replication and transcription. By blocking them, ofloxacin prevents bacterial cells from multiplying, leading to a bactericidal effect against a broad range of ocular pathogens.

The dosing regimen for Ofloxa-Vision Sine is determined by the prescribing clinician based on the specific infection, severity, patient age and response to therapy. The prescriber will provide exact instructions on the number of drops, frequency and duration of treatment.

The pregnancy category for ofloxacin is not definitively established, and safety data are limited. Caution is advised when prescribing to pregnant or nursing women; the prescriber should weigh potential benefits against possible risks and consider alternative therapies if appropriate.

To place an order, visit the product page on gnhindia.com, enter the required quantity and submit the enquiry form. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and the necessary import documentation.

Ofloxa-Vision Sine contains ofloxacin, a broad‑spectrum fluoroquinolone that offers strong activity against both Gram‑negative and Gram‑positive ocular pathogens. Compared with older agents such as ciprofloxacin, ofloxacin often provides similar efficacy with a convenient dosing schedule and a favorable safety profile, though individual choice depends on local resistance patterns and clinician preference.

Store the ophthalmic solution at room temperature, preferably below 25 °C. Keep the bottle in its original packaging, protect it from direct light and moisture, and ensure the cap is tightly closed when not in use. Do not freeze the product.

The medication is applied as eye drops. The patient should wash their hands, tilt the head back, pull down the lower eyelid to create a small pocket, and instill the prescribed number of drops into the conjunctival sac. The eye should be closed gently for a few seconds to allow absorption, and contact lenses should be avoided for at least 15 minutes.

Serious adverse events, although rare, include corneal ulceration or worsening of existing corneal lesions, severe allergic reactions such as swelling, itching or rash, and anaphylaxis, which requires immediate medical attention. Patients should be instructed to seek urgent care if they experience any of these symptoms.

Individuals with a known hypersensitivity to ofloxacin, other fluoroquinolones, or any component of the formulation should avoid using Ofloxa-Vision Sine. It is also contraindicated in patients who have experienced severe ocular reactions to fluoroquinolone eye drops in the past.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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