Product image of Ofloxacin Al (Ofloxacin) supplied by GNH India

Ofloxacin Al

Active Ingredient:
Ofloxacin
Origin:
EU

Ofloxacin Al (Ofloxacin)

Ofloxacin, the active ingredient in Ofloxacin Al, is a fluoroquinolone presented as an oral dosage form for oral use. It treats bacterial infections such as urinary tract, respiratory, skin and gastrointestinal infections in adult patients.

GNH India supplies Ofloxacin Al as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Aliud Pharma Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Ofloxacin is a broad‑spectrum antibacterial indicated for infections of several organ systems.
  • Urinary tract infections: eradicates common uropathogens and resolves symptoms.
  • Respiratory tract infections: treats community‑acquired pneumonia and bronchitis caused by susceptible bacteria.
  • Skin and soft tissue infections: clears cellulitis, abscesses and wound infections.
  • Gastrointestinal infections: effective against bacterial dysentery and enteric pathogens.

How It Works

  • Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA supercoiling and replication. By binding to these enzymes, it prevents DNA synthesis and transcription, leading to bacterial cell death. This bactericidal action is effective against a wide range of Gram‑negative and Gram‑positive organisms.

Side Effects

Adverse reactions may occur with Ofloxacin use.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, often self‑limiting.
  • Headache: transient cranial discomfort.
  • Dizziness: occasional vertigo or light‑headedness.
  • Abdominal pain: cramping or discomfort.
  • Rash: mild skin erythema.

Serious or Rare Side Effects

  • Tendon rupture: especially Achilles, may occur without warning.
  • QT interval prolongation: risk of cardiac arrhythmia.
  • Severe allergic reactions: anaphylaxis, angioedema.
  • Clostridioides difficile infection: severe colitis.
  • Hepatic dysfunction: elevated liver enzymes or hepatitis.
  • Peripheral neuropathy: sensory loss or tingling.

Precautions & Warnings

  • Before prescribing Ofloxacin, clinicians should consider patient‑specific factors.
  • Assess renal function: adjust dosing in impaired clearance.
  • Monitor for tendon pain: discontinue if signs of tendinopathy appear.
  • Avoid concurrent NSAIDs: increased risk of gastrointestinal bleeding.
  • Use with caution in elderly: higher incidence of adverse events.
  • Do not use in patients with known hypersensitivity to fluoroquinolones.
  • Store at ambient temperature: keep in original container, protect from moisture.

Avoid Interactions

Ofloxacin may interact with several medicines; awareness of interaction severity is essential.

Major Interactions (Avoid)

  • Tizanidine: may cause profound hypotension.
  • Warfarin: increased anticoagulant effect, risk of bleeding.
  • Theophylline: elevated plasma levels, potential toxicity.
  • Antacids containing magnesium or aluminum: reduce Ofloxacin absorption.
  • Cyclosporine: increased risk of nephrotoxicity.

Moderate Interactions (Monitor Closely)

  • Nonsteroidal anti‑inflammatory drugs: heightened gastrointestinal risk.
  • Corticosteroids: potential for tendon rupture.
  • Oral contraceptives: reduced efficacy, advise backup method.
  • Diabetic agents: possible alteration of glucose control.
  • Other fluoroquinolones: additive QT prolongation risk.

Frequently Asked Questions

Ofloxacin Al is indicated for bacterial infections of the urinary tract, respiratory system, skin and soft tissues, and the gastrointestinal tract. It is prescribed when the causative organisms are known or suspected to be susceptible to fluoroquinolones.

Ofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By inhibiting these targets, the drug prevents bacterial cell division and leads to bacterial death, providing a bactericidal effect.

The dosage of Ofloxacin Al is determined by the prescribing clinician based on the infection type, severity, patient age, weight, and renal function. Patients should follow the exact regimen provided by their healthcare professional.

The safety of Ofloxacin in pregnancy and lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and after consultation with a qualified healthcare provider.

To order Ofloxacin Al, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Ofloxacin shares the class‑wide mechanism of DNA gyrase inhibition but differs in its spectrum of activity and pharmacokinetic profile. Compared with ciprofloxacin, Ofloxacin often has similar efficacy but may offer dosing convenience for certain infections; however, selection should be based on susceptibility data and patient factors.

Ofloxacin Al should be stored at ambient temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Ofloxacin Al is administered orally, usually as a tablet or suspension, and should be taken with a full glass of water. It can be taken with or without food, but patients should avoid taking it simultaneously with antacids or supplements containing magnesium, aluminum, calcium or iron.

Serious risks include tendon rupture, especially in the Achilles tendon, QT interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, and peripheral neuropathy. Patients should be instructed to seek immediate medical attention if these events occur.

Ofloxacin Al is contraindicated in individuals with a known hypersensitivity to Ofloxacin, other fluoroquinolones, or any component of the formulation. It should also be avoided in patients with a history of tendon disorders related to fluoroquinolone therapy and in those with certain cardiac conditions that predispose to QT prolongation.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Ofloxacin

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT