Ofloxacin-Ophtal Kombipackung Dr. Gerhard Mann Chem.-Pharm. Fabrik (Ofloxacin)

Ofloxacin belongs to the fluoroquinolone class and exerts its antibacterial effect by inhibiting the bacterial enzymes DNA gyrase and topoisomerase IV. These enzymes are essential for DNA replication and transcription. By blocking them, Ofloxacin prevents bacterial cell division, leading to bacterial death and resolution of the infection.

The specific dosing regimen for Ofloxacin‑Ophtal is determined by the prescribing clinician based on the type and severity of the infection, patient age, and response to therapy. Typical regimens involve instilling the prescribed number of drops into the affected eye(s) at defined intervals. Patients should follow the exact instructions provided by their eye care professional.

Safety data for Ofloxacin‑Ophtal in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant. Healthcare providers will assess the individual situation and may recommend alternative treatments when appropriate. Pregnant or nursing patients should discuss all options with their physician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide. After the enquiry, the sales team will verify trade or institutional credentials, then provide pricing, availability, shipping details (including any required temperature control) and assist with import documentation.

Ofloxacin‑Ophtal is a fluoroquinolone, offering broad‑spectrum activity against Gram‑negative and Gram‑positive ocular pathogens. Compared with older agents such as chloramphenicol or macrolides, fluoroquinolones generally provide faster bacterial eradication and lower resistance rates. However, selection of therapy should consider local resistance patterns, patient tolerance and specific organism susceptibility.

The product should be stored at room temperature, preferably below 25 °C, in its original container. Protect the container from light and moisture to maintain stability. Do not freeze the solution. Keep the vial tightly closed when not in use and discard any remaining product after the recommended period after opening, as indicated on the label.

Ofloxacin‑Ophtal is applied as an eye drop. The patient should wash their hands, tilt the head back, and gently pull down the lower eyelid to create a small pocket. One or more drops are placed into the conjunctival sac as prescribed, avoiding contact with the eye or eyelid. The patient should close the eye gently for a few seconds to allow distribution.

Serious risks include severe allergic reactions such as anaphylaxis, corneal ulceration or perforation, and rare systemic hypersensitivity syndromes like Stevens‑Johnson syndrome. Vision loss may occur if a serious ocular complication develops. Patients should seek immediate medical attention if they experience intense eye pain, sudden vision changes, swelling, or signs of an allergic reaction.

Individuals with a known hypersensitivity to Ofloxacin, other fluoroquinolones, or any component of the ophthalmic formulation should avoid using the product. It is also contraindicated in patients who have experienced severe adverse reactions to similar eye medications. Clinicians should assess each patient’s medical history before prescribing.