Product image of Ofloxacin Stada (Ofloxacin) supplied by GNH India

Ofloxacin Stada

Active Ingredient:
Ofloxacin
Origin:
EU

Ofloxacin Stada (Ofloxacin)

Ofloxacin, the active ingredient in Ofloxacin Stada, is a fluoroquinolone antibiotic presented as an oral tablet for oral use. It treats a variety of bacterial infections in adults and children as prescribed by a healthcare professional.

GNH India supplies Ofloxacin Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Stada Arzneimittel Gmbh

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Indications & Clinical Uses

Ofloxacin is a fluoroquinolone antibiotic used to treat infections caused by susceptible bacteria.

  • Urinary tract infection: eradicates the causative Gram‑negative and Gram‑positive organisms, relieving symptoms and preventing recurrence.
  • Respiratory tract infection: eliminates pathogens such as Haemophilus influenzae and Streptococcus pneumoniae, improving breathing and cough.
  • Skin and soft‑tissue infection: clears susceptible Staphylococcus and Streptococcus species, promoting wound healing.
  • Gastrointestinal infection: targets enteric pathogens like Shigella, reducing diarrhea and abdominal pain.
  • Sexually transmitted infection (gonorrhoea): kills Neisseria gonorrhoeae strains, aiding resolution of urethritis and cervicitis.

How It Works

  • Ofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA supercoiling and replication. By binding to these enzymes, it prevents DNA synthesis and transcription, leading to bacterial cell death. This bactericidal action is effective against a broad spectrum of Gram‑negative and Gram‑positive organisms.

Side Effects

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: occasional light‑headedness.
  • Rash: mild skin irritation or redness.

Serious or Rare Side Effects

  • Tendon rupture: sudden pain or swelling in tendons, especially the Achilles.
  • QT interval prolongation: cardiac rhythm disturbances.
  • Severe allergic reaction: anaphylaxis with breathing difficulty.
  • Central nervous system effects: seizures or severe confusion.
  • Hepatotoxicity: elevated liver enzymes or jaundice.

Precautions & Warnings

Before using Ofloxacin Stada, consider the following precautions:

  • Allergy assessment: avoid if known hypersensitivity to fluoroquinolones.
  • Tendon health: discontinue if tendon pain or inflammation occurs.
  • Cardiac monitoring: caution in patients with known QT prolongation.
  • Renal function: adjust use in severe renal impairment as directed by a clinician.
  • Pregnancy and lactation: use only if clearly needed and prescribed.
  • Store at ambient temperature: keep below 25°C in the original packaging, protected from moisture and direct sunlight.

Avoid Interactions

Ofloxacin Stada may interact with several medicines.

Major Interactions (Avoid)

  • Antacids containing aluminum or magnesium: markedly reduce Ofloxacin absorption.
  • Warfarin: may increase anticoagulant effect, raising bleeding risk.
  • Cyclosporine: heightened risk of neurotoxicity.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory drugs (NSAIDs): may increase risk of central nervous system stimulation.
  • Theophylline: potential for increased serum theophylline levels.
  • Corticosteroids: may elevate risk of tendon rupture.

Frequently Asked Questions

Ofloxacin Stada is prescribed to treat a range of bacterial infections, including urinary tract infections, respiratory tract infections, skin and soft‑tissue infections, gastrointestinal infections, and certain sexually transmitted infections such as gonorrhoea. It works against susceptible Gram‑negative and Gram‑positive bacteria.

Ofloxacin belongs to the fluoroquinolone class and works by inhibiting bacterial DNA gyrase and topoisomerase IV. These enzymes are essential for DNA replication and transcription. By blocking them, Ofloxacin prevents bacterial cells from multiplying, leading to their death.

The dose of Ofloxacin Stada is determined by the prescribing clinician based on the type and severity of the infection, the patient’s age, weight, kidney function, and any other relevant medical conditions. Patients should follow the exact regimen provided by their healthcare professional.

The safety of Ofloxacin during pregnancy or lactation has not been definitively established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To order Ofloxacin Stada, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ofloxacin shares the same mechanism of action as other fluoroquinolones but differs in its spectrum of activity, pharmacokinetic profile, and dosing convenience. Compared with agents like ciprofloxacin, Ofloxacin often offers similar efficacy with a slightly broader Gram‑positive coverage, though individual choice depends on infection type and susceptibility patterns.

Store Ofloxacin Stada at ambient temperature, preferably below 25 °C. Keep the tablets in the original blister pack or container, protect them from moisture, heat and direct sunlight, and keep out of reach of children.

Ofloxacin Stada is taken orally, usually with a full glass of water. It can be taken with or without food, but if an antacid is required, it should be spaced at least two hours apart to avoid reduced absorption.

Serious risks include tendon rupture (especially the Achilles tendon), QT interval prolongation leading to cardiac arrhythmias, severe allergic reactions such as anaphylaxis, central nervous system effects like seizures, and potential liver injury. Patients should seek immediate medical attention if they experience any of these symptoms.

Ofloxacin Stada should not be used by individuals with a known hypersensitivity to fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, patients with prolonged QT interval, or anyone currently taking medications that have major contraindicated interactions, unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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