Product image of Ofloxacine Sandoz (Ofloxacin) supplied by GNH India

Ofloxacine Sandoz

Active Ingredient:
Ofloxacin
Origin:
EU

Ofloxacine Sandoz (Ofloxacin)

Ofloxacin, the active ingredient in Ofloxacine Sandoz, is a fluoroquinolone antibiotic presented as a tablet for oral use. It treats a variety of bacterial infections in adults and children, including urinary, respiratory and skin infections.\n\nGNH India supplies Ofloxacine Sandoz as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Sandoz

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Ofloxacin is a broad‑spectrum fluoroquinolone used to manage bacterial infections across several organ systems.\n\n- Urinary tract infection: eradicates susceptible Gram‑negative and Gram‑positive bacteria, promoting rapid symptom relief.\n- Acute bacterial sinusitis: reduces bacterial load, aiding recovery of sinus mucosa.\n- Acute exacerbation of chronic bronchitis: targets common respiratory pathogens, improving airflow and cough.\n- Skin and soft‑tissue infection: combats Staphylococcus and Streptococcus species, facilitating wound healing.\n- Uncomplicated gonorrhoea: eliminates Neisseria gonorrhoeae, preventing disease progression.

How It Works

  • Ofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By stabilizing the enzyme‑DNA complex, it prevents strand re‑ligation, leading to lethal double‑strand breaks and bacterial cell death. This bactericidal action is effective against a wide range of Gram‑negative and Gram‑positive organisms.

Side Effects

  • Common Side Effects:\n- Nausea\n- Diarrhoea\n- Headache\n- Dizziness\n- Abdominal pain\n- Rash\n\nSerious or Rare Side Effects:\n- Tendon rupture or tendinitis\n- QT interval prolongation leading to arrhythmia\n- Severe allergic reactions (anaphylaxis)\n- Clostridioides difficile‑associated diarrhoea\n- Hepatic dysfunction\n- Photosensitivity

Precautions & Warnings

  • Before prescribing Ofloxacine Sandoz, consider the following precautions.\n\n- Renal impairment: adjust dose according to renal function.\n- History of tendon disorders: avoid use or monitor closely for tendon pain.\n- Pregnancy and lactation: contraindicated unless benefits outweigh risks.\n- Concomitant QT‑prolonging drugs: monitor cardiac rhythm.\n- Use in children: follow pediatric dosing guidelines.\n- Store at room temperature: keep in original container, protect from moisture and light.

Avoid Interactions

  • Ofloxacin may interact with several medicines; review patient medication lists carefully.\n\nMajor Interactions (Avoid):\n- Tizanidine: co‑administration can cause severe hypotension.\n- Non‑steroidal anti‑inflammatory drugs (NSAIDs): increased risk of central nervous system stimulation.\n- Antacids containing magnesium or aluminium: reduce Ofloxacin absorption.\n\nModerate Interactions (Monitor Closely):\n- Other fluoroquinolones (e.g., ciprofloxacin): additive QT prolongation risk.\n- Warfarin: may enhance anticoagulant effect, requiring INR monitoring.\n- Theophylline: Ofloxacin can increase plasma theophylline levels, necessitating dose adjustment.

Frequently Asked Questions

Ofloxacine Sandoz, containing Ofloxacin, is indicated for a range of bacterial infections such as urinary tract infections, acute bacterial sinusitis, exacerbations of chronic bronchitis, skin and soft‑tissue infections, and uncomplicated gonorrhoea. It is prescribed when the causative bacteria are known or suspected to be susceptible to fluoroquinolones.

Ofloxacin belongs to the fluoroquinolone class and works by inhibiting bacterial DNA gyrase and topoisomerase IV. These enzymes are essential for DNA replication and transcription. By blocking them, Ofloxacin prevents bacterial cells from reproducing, leading to cell death and resolution of the infection.

The dosage of Ofloxacine Sandoz is determined by the prescribing clinician based on the type and severity of infection, patient age, renal function, and other clinical factors. Healthcare professionals set the appropriate dose and treatment duration according to established guidelines.

Ofloxacin is generally contraindicated during pregnancy and lactation unless the potential benefit justifies the risk to the fetus or infant. It crosses the placenta and may be excreted in breast milk, so clinicians evaluate alternatives before prescribing to pregnant or nursing women.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Ofloxacine Sandoz offers a broad spectrum of activity similar to other fluoroquinolones, but its pharmacokinetic profile, dosing convenience, and specific bacterial susceptibility patterns may differ. Clinicians choose it based on local resistance data, patient tolerance, and the infection site, balancing efficacy with safety considerations.

Store Ofloxacine Sandoz tablets at room temperature, below 25 °C, in the original packaging to protect from moisture and light. Do not store in bathrooms or near heat sources, and keep out of reach of children.

Ofloxacine Sandoz is administered orally, typically as a tablet taken with a full glass of water. It may be taken with or without food, but patients should avoid concurrent intake of antacids containing magnesium or aluminium, which can impair absorption.

Serious risks include tendon rupture or tendinitis, especially in older adults or those on corticosteroids; QT interval prolongation leading to cardiac arrhythmias; severe allergic reactions such as anaphylaxis; and Clostridioides difficile‑associated diarrhoea. Patients should be advised to report any sudden joint pain, palpitations, or severe rash promptly.

Ofloxacine Sandoz should be avoided in patients with a known hypersensitivity to Ofloxacin or other fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, pregnant or breastfeeding women unless absolutely necessary, and individuals taking medications that significantly prolong the QT interval without careful monitoring.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.