Product image of Oftagel (Carbomer 974p) supplied by GNH India

Oftagel

Active Ingredient:
Carbomer 974p
Origin:
EU

Oftagel (Carbomer 974p)

Carbomer 974P, the active ingredient in Oftagel, is an excipient presented as a ocular lubricant for ophthalmic use. It forms a protective gel layer on the eye surface, helping to retain moisture and alleviate dryness. GNH India supplies Oftagel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and ophthalmology clinics worldwide.

GNH India supplies Oftagel as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres and ophthalmology clinics worldwide.

Manufacturer / TM Owner

Santen Oy

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Indications & Clinical Uses

Oftagel is an ophthalmic gel that provides lubrication for the ocular surface and supports tear film stability.

  • Dry eye syndrome: helps maintain ocular surface moisture and comfort.
  • Post‑operative eye care: assists in protecting the cornea after surgical procedures.
  • Contact lens wear: reduces irritation and dryness associated with lens use.

How It Works

  • Carbomer 974P is a high‑molecular‑weight polymer that swells in aqueous media to create a viscous, bio‑adhesive gel. When applied to the eye, it forms a thin, lubricating film that adheres to the ocular surface, reducing tear evaporation and enhancing the stability of the tear film without pharmacologic activity.

Side Effects

Oftagel is generally well tolerated, but ocular preparations can cause local reactions.

Common Side Effects

  • Transient blurred vision: brief loss of visual clarity after application.
  • Mild ocular irritation: temporary stinging or burning sensation.
  • Foreign body sensation: feeling of something in the eye.
  • Redness: mild conjunctival hyperemia.
  • Tearing: increased lacrimation.
  • Eye discomfort: general feeling of unease.

Serious or Rare Side Effects

  • Allergic contact dermatitis: localized skin reaction around the eye.
  • Severe eye inflammation: marked conjunctival or corneal inflammation.
  • Persistent visual disturbance: lasting blurred vision beyond the initial period.
  • Corneal ulceration: rare breakdown of corneal epithelium.
  • Anaphylaxis: extremely rare systemic hypersensitivity reaction.
  • Vision loss: very rare, potentially sight‑threatening event.

Precautions & Warnings

When using Oftagel, consider the following safety measures:

  • Avoid contamination: use a new sterile applicator for each dose.
  • Contact lens wearers: remove lenses before application and re‑insert after.
  • Pre‑existing eye conditions: consult an eye‑care professional if you have active infection or inflammation.
  • Pediatric use: only use under supervision of a qualified practitioner.
  • Pregnancy and lactation: discuss with a healthcare provider before use.
  • Store at ambient temperature: keep below 25°C, protect from direct sunlight and moisture.

Avoid Interactions

Oftagel may interact with other ophthalmic products, potentially affecting comfort or efficacy.

Major Interactions (Avoid)

  • Concurrent use with preservative‑rich eye drops: may increase irritation.
  • Antibiotic eye ointments: can interfere with gel formation.

Moderate Interactions (Monitor Closely)

  • Antihistamine eye drops: may alter tear film dynamics.
  • Steroid eye drops: monitor for additive drying effects.
  • Contact lens solutions: ensure compatibility before combined use.

Frequently Asked Questions

Oftagel is an ophthalmic gel formulated to lubricate the ocular surface. It is used to relieve dry eye symptoms, support post‑operative eye care, and reduce irritation for contact lens wearers by providing a protective, moisture‑retaining film on the eye.

Carbomer 974P is a high‑molecular‑weight polymer that absorbs water and forms a viscous gel. When applied to the eye, it creates a thin, adhesive layer that reduces tear evaporation, stabilises the tear film and improves comfort without delivering active pharmacologic agents.

The dosage of Oftagel is determined by the prescribing eye‑care professional based on the individual’s condition and response. Typically, a small amount is instilled onto the ocular surface as needed, following the clinician’s instructions.

Oftagel contains an inert excipient and is generally considered low risk, but safety has not been fully established in pregnancy or lactation. Women who are pregnant, planning pregnancy, or breastfeeding should discuss use with their healthcare provider.

To order Oftagel, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Oftagel’s primary distinction is its Carbomer‑based gel matrix, which offers longer residence time on the eye compared with many liquid artificial tears. This can provide extended relief for dry eye and post‑operative care, though choice of lubricant should be individualized based on patient tolerance and specific clinical needs.

Oftagel should be stored at ambient temperature, preferably below 25 °C, in its original sealed container. Protect the product from direct sunlight, moisture and extreme temperature fluctuations to maintain sterility and gel integrity.

Oftagel is applied topically to the eye using a sterile applicator. The patient places a small amount of gel onto the lower conjunctival sac, typically after washing hands, and may blink gently to spread the gel evenly across the ocular surface.

Serious but rare risks include severe eye inflammation, corneal ulceration, allergic contact dermatitis and, in extremely rare cases, anaphylaxis or vision loss. Any signs of intense irritation, persistent redness, pain or visual changes should prompt immediate medical evaluation.

Individuals with known hypersensitivity to Carbomer or any component of the formulation should avoid using Oftagel. It is also contraindicated in eyes with active infection or severe inflammation unless directed by an eye‑care professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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