Product image of Oftan (Timolol) supplied by GNH India

Oftan

Active Ingredient:
Timolol
Origin:
EU

Oftan (Timolol)

Timolol, the active ingredient in Oftan, is a beta blocker presented as an ophthalmic solution for ocular use. It treats open‑angle glaucoma and ocular hypertension by lowering intra‑ocular pressure.

GNH India supplies Oftan as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Santen Oy

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Indications & Clinical Uses

  • Timolol is used in the management of ocular conditions that involve elevated intra‑ocular pressure.
  • Open‑angle glaucoma: reduces intra‑ocular pressure to slow disease progression.
  • Ocular hypertension: lowers intra‑ocular pressure to prevent development of glaucoma.
  • Secondary glaucoma: helps control pressure when other causes are present.

How It Works

  • Timolol acts as a non‑selective beta‑adrenergic receptor antagonist. By blocking β1 and β2 receptors in the ciliary body, it decreases aqueous humor production, leading to a reduction in intra‑ocular pressure and helping to manage glaucoma and ocular hypertension.

Side Effects

Timolol may cause ocular and systemic adverse reactions.

Common Side Effects

  • Burning or stinging sensation in the eye
  • Blurred vision
  • Dry eye or reduced tear production
  • Conjunctival hyperemia (redness)
  • Temporary visual disturbances
  • Mild headache

Serious or Rare Side Effects

  • Bradycardia or heart block
  • Systemic hypotension
  • Bronchospasm or worsening asthma
  • Severe allergic reaction (angio‑edema, anaphylaxis)
  • Cardiac failure or worsening heart disease
  • Depression or mood changes

Precautions & Warnings

  • Timolol requires careful assessment before and during therapy.
  • Assess cardiovascular status: check for bradycardia, heart block, or heart failure.
  • Review respiratory history: avoid in patients with asthma or severe COPD.
  • Monitor blood pressure: watch for systemic hypotension.
  • Avoid concurrent non‑selective beta‑blockers: risk of additive cardiac effects.
  • Store at room temperature: keep in original container, protect from light and moisture.

Avoid Interactions

Timolol can interact with other systemic and ocular agents.

Major Interactions (Avoid)

  • Systemic non‑selective beta‑blockers (e.g., propranolol): additive cardiac depression.
  • Calcium channel blockers (e.g., verapamil): increased risk of AV block.
  • Antiarrhythmic drugs (e.g., amiodarone): enhanced bradycardia.

Moderate Interactions (Monitor Closely)

  • Topical adrenergic agonists (e.g., epinephrine eye drops): reduced efficacy.
  • Other ocular hypotensives (e.g., prostaglandin analogs): additive pressure‑lowering effect.
  • Systemic antihypertensives: may potentiate hypotensive response.

Frequently Asked Questions

Oftan contains timolol, a beta‑blocker eye drop used to lower intra‑ocular pressure in patients with open‑angle glaucoma or ocular hypertension, helping to prevent optic nerve damage and vision loss.

Timolol blocks β‑adrenergic receptors in the ciliary body, reducing the production of aqueous humor. This decrease in fluid formation lowers intra‑ocular pressure, which is essential in managing glaucoma and ocular hypertension.

The prescribed dose of Oftan is determined by the treating ophthalmologist based on the patient’s condition and response. Typically, one drop is instilled in the affected eye(s) once or twice daily, but the exact regimen must follow the prescriber’s instructions.

Safety data for timolol in pregnancy and lactation are limited. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To order Oftan, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Oftan (timolol) is a non‑selective beta‑blocker, whereas many alternatives are prostaglandin analogues or carbon‑ic anhydrase inhibitors. Timolol primarily reduces aqueous humor production, while prostaglandins increase outflow. Choice of therapy depends on efficacy, tolerance, patient comorbidities and physician preference.

Oftan should be stored at room temperature, below 25 °C, in its original container. Keep the bottle tightly closed, protect it from light and moisture, and discard any solution that appears discolored or contains particles.

Oftan is applied as an eye drop. The patient should wash hands, tilt the head back, pull down the lower eyelid to form a pocket, and place one drop into the conjunctival sac. Close the eye gently and avoid blinking excessively for a few minutes.

Serious risks include systemic bradycardia, hypotension, bronchospasm in susceptible individuals, and severe allergic reactions such as angio‑edema. Patients should seek immediate medical attention if they experience chest pain, difficulty breathing, rapid weight gain, or signs of an allergic reaction.

Oftan is contraindicated in patients with known hypersensitivity to timolol or other beta‑blockers, those with severe sinus bradycardia, second‑ or third‑degree heart block, decompensated heart failure, or uncontrolled asthma/COPD. A healthcare professional should evaluate suitability before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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