Product image of Oftaquix (Levofloxacin Hemihydrate) supplied by GNH India

Oftaquix

Active Ingredient:
Levofloxacin Hemihydrate
Origin:
EU

Oftaquix (Levofloxacin Hemihydrate)

Levofloxacin Hemihydrate, the active ingredient in Oftaquix, is a fluoroquinolone antibiotic presented as a oral tablet for systemic use. It treats a variety of bacterial infections in adults and children when prescribed by a healthcare professional.

GNH India supplies Oftaquix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Santen Oy

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Indications & Clinical Uses

Oftaquix is a broad‑spectrum antibacterial that is used for infections affecting several organ systems.

  • Acute bacterial sinusitis: helps relieve sinus inflammation and discharge caused by susceptible bacteria.
  • Uncomplicated urinary tract infection: eradicates the causative uropathogens and reduces urinary symptoms.
  • Community‑acquired pneumonia: targets the typical respiratory pathogens to improve lung function and reduce fever.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication, transcription and repair. By blocking these enzymes, the drug prevents bacterial cells from proliferating and leads to bacterial cell death, providing a bactericidal effect against susceptible Gram‑negative and Gram‑positive organisms.

Side Effects

Levofloxacin may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea or vomiting
  • Diarrhea
  • Headache
  • Dizziness
  • Photosensitivity rash
  • Abdominal pain

Serious or Rare Side Effects

  • Tendon rupture or inflammation
  • Peripheral neuropathy
  • Severe allergic reactions (anaphylaxis, Stevens‑Johnson syndrome)
  • QT interval prolongation
  • Clostridioides difficile‑associated colitis
  • Hepatotoxicity

Precautions & Warnings

When prescribing Levofloxacin, clinicians should consider several safety aspects.

  • Renal impairment: adjust dose based on creatinine clearance.
  • History of tendon disorders: avoid use in patients with recent tendon injury.
  • Cardiac risk: monitor QT interval in patients with known arrhythmias.
  • Pregnancy and lactation: use only if clearly needed, after risk‑benefit assessment.
  • Concomitant CNS active drugs: watch for increased seizures.
  • Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Levofloxacin can interact with a variety of medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Antacids containing magnesium or aluminum: reduce levofloxacin absorption.
  • Warfarin: may increase anticoagulant effect and bleeding risk.
  • NSAIDs (non‑selective): heightened risk of central nervous system stimulation.

Moderate Interactions (Monitor Closely)

  • Theophylline: may increase serum theophylline levels.
  • Cyclosporine: potential for increased nephrotoxicity.
  • Oral hypoglycemics: may enhance hypoglycaemic effect.

Frequently Asked Questions

Oftaquix contains levofloxacin, a fluoroquinolone antibiotic that is prescribed to treat a range of bacterial infections such as acute sinusitis, uncomplicated urinary tract infections and community‑acquired pneumonia, when the infecting organisms are known or expected to be susceptible.

Levofloxacin blocks bacterial DNA gyrase and topoisomerase IV, enzymes that are required for DNA replication and transcription. Inhibiting these enzymes stops bacterial cells from multiplying, leading to a bactericidal effect against susceptible Gram‑positive and Gram‑negative bacteria.

The dosage of Oftaquix is determined by the prescribing clinician based on the type and severity of infection, patient age, renal function and other clinical factors. Physicians set the dose and duration according to approved guidelines and individual patient needs.

Levofloxacin is classified as a pregnancy‑category C drug. It should be used only when the potential benefit justifies the potential risk to the fetus. Breastfeeding mothers should consult a healthcare professional, as the drug can be excreted in breast milk.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Levofloxacin offers broad‑spectrum coverage against many Gram‑negative and Gram‑positive pathogens and has the convenience of once‑daily oral dosing. Compared with older fluoroquinolones, it provides higher potency against certain respiratory and urinary pathogens, though safety considerations such as tendon risk remain similar across the class.

Oftaquix tablets should be stored below 25 °C in their original packaging, protected from moisture and direct sunlight. Maintaining these conditions helps preserve the tablet’s stability and potency throughout its shelf life.

Oftaquix is supplied as an oral tablet and is taken by mouth with or without food, as directed by the prescribing clinician. The tablet should be swallowed whole with an adequate amount of water.

Serious adverse reactions can include tendon rupture or inflammation, peripheral neuropathy, severe allergic reactions such as Stevens‑Johnson syndrome, QT‑interval prolongation and Clostridioides difficile‑associated colitis. Patients should be advised to seek immediate medical attention if they experience any of these symptoms.

Levofloxacin is contraindicated in patients with a known hypersensitivity to fluoroquinolones, those with a history of tendon disorders related to fluoroquinolone use, and individuals with certain cardiac conditions that predispose them to QT prolongation. Clinicians should evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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