Product image of Oftaquix (Levofloxacin Hemihydrate) supplied by GNH India

Oftaquix

Active Ingredient:
Levofloxacin Hemihydrate
Origin:
EU

Oftaquix (Levofloxacin Hemihydrate)

Levofloxacin, the active ingredient in Oftaquix, is a fluoroquinolone antibiotic presented as an ophthalmic solution for ocular use. It treats bacterial conjunctivitis and bacterial keratitis by targeting susceptible eye pathogens in patients who need topical antimicrobial therapy, and is formulated for convenient instillation.

GNH India supplies Oftaquix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies, transplant centres and clinics worldwide, ensuring quality, regulatory compliance and reliable logistics across global markets. The company adheres to stringent manufacturing standards and provides comprehensive documentation for regulatory submissions.

Manufacturer / TM Owner

Santen Oy

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Indications & Clinical Uses

Oftaquix, a fluoroquinolone ophthalmic antibiotic, is used to treat bacterial infections of the eye.

  • Bacterial conjunctivitis: reduces bacterial load, relieving redness, discharge and discomfort.
  • Bacterial keratitis: eradicates causative organisms and supports corneal healing.
  • Acute bacterial ocular infection (e.g., post‑traumatic): controls bacterial proliferation to prevent worsening of the infection.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes essential for DNA replication and transcription. By binding to these targets, it prevents bacterial DNA synthesis, leading to cell death and effective eradication of susceptible ocular pathogens.

Side Effects

Common Side Effects

  • Eye irritation: mild burning or stinging after instillation.
  • Redness: transient conjunctival hyperemia.
  • Tearing: increased lacrimation.
  • Blurred vision: temporary visual disturbance.
  • Foreign body sensation: feeling of grit in the eye.
  • Photophobia: sensitivity to light.

Serious or Rare Side Effects

  • Allergic reaction: swelling, itching, or rash around the eye.
  • Stevens‑Johnson syndrome: severe skin and mucous membrane involvement.
  • Corneal ulceration: worsening of corneal lesions.
  • Vision loss: rare but potentially irreversible.
  • Severe ocular inflammation: marked edema or hypopyon.
  • Systemic fluoroquinolone toxicity: rare systemic effects with extensive use.

Precautions & Warnings

Before using Oftaquix, consider the following precautions:

  • Allergy assessment: verify no known hypersensitivity to fluoroquinolones.
  • Contact lens use: advise removal of lenses before and for a short period after instillation.
  • Pregnancy and lactation: reserve for cases where benefit outweighs potential risk.
  • Concurrent ocular medications: avoid mixing with other eye drops unless directed by a clinician.
  • Prolonged therapy: monitor for signs of systemic absorption or ocular toxicity.
  • Store at room temperature: keep in the original container, protect from light and moisture.

Avoid Interactions

Levofloxacin may interact with other ophthalmic or systemic agents.

Major Interactions (Avoid)

  • Systemic fluoroquinolones: concurrent use can increase risk of additive toxicity.
  • Corticosteroid eye drops: may heighten risk of corneal perforation.
  • Anticholinergic agents: can reduce ocular absorption of the antibiotic.

Moderate Interactions (Monitor Closely)

  • Non‑steroidal anti‑inflammatory eye drops: may affect corneal healing.
  • Herbal supplements containing quinine: monitor for QT‑interval prolongation.

Frequently Asked Questions

Oftaquix is a prescription ophthalmic solution containing levofloxacin, used to treat bacterial eye infections such as bacterial conjunctivitis and bacterial keratitis. It works by eliminating susceptible bacteria on the ocular surface, helping to resolve redness, discharge, and discomfort associated with these infections.

Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By blocking these targets, the drug prevents bacterial cells from multiplying, leading to bacterial death and clearance of the infection in the eye.

The dosing regimen for Oftaquix is determined by the prescribing clinician based on the severity of the infection, patient age, and response to therapy. The prescriber will specify the number of drops, frequency, and duration appropriate for each individual case.

Levofloxacin is generally reserved for use in pregnancy or lactation only when the potential benefit justifies any potential risk to the fetus or infant. Healthcare providers should evaluate the risk‑benefit profile before prescribing this medication to pregnant or nursing women.

To request Oftaquix, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Oftaquix (levofloxacin) belongs to the fluoroquinolone class, offering broad‑spectrum activity against Gram‑negative and Gram‑positive ocular pathogens. Compared with older agents such as ciprofloxacin, levofloxacin often provides enhanced potency and a lower dosing frequency, while maintaining a similar safety profile.

Oftaquix should be stored at room temperature, protected from light and moisture. Keep the vial in its original packaging and ensure the cap is tightly closed when not in use. Do not freeze the solution, and discard any product that appears discolored or contaminated.

The medication is applied as eye drops. The patient should wash hands, tilt the head back, pull down the lower eyelid to create a pocket, and instill the prescribed number of drops. The eye should be closed gently for a few seconds to allow absorption, avoiding blinking or rubbing.

Serious risks, though rare, include severe allergic reactions, Stevens‑Johnson syndrome, corneal ulceration, and vision loss. Patients should seek immediate medical attention if they experience swelling, rash, worsening eye pain, or any sudden change in vision after using the drops.

Individuals with a known hypersensitivity to levofloxacin, other fluoroquinolones, or any component of the formulation should avoid using Oftaquix. Caution is also advised for patients with a history of tendon disorders or those taking systemic fluoroquinolones, unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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