Product image of Oftaquix (Levofloxacin Hemihydrate) supplied by GNH India

Oftaquix

Active Ingredient:
Levofloxacin Hemihydrate
Origin:
EU

Oftaquix (Levofloxacin Hemihydrate)

Levofloxacin, the active ingredient in Oftaquix, is a fluoroquinolone antibiotic presented as a tablet for oral use. It is indicated for the treatment of various bacterial infections in adults and children, including respiratory, urinary and skin infections, when prescribed by a qualified clinician. It is formulated for systemic absorption and is available in multiple dosage strengths to match clinical requirements.

GNH India supplies Oftaquix as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides regulatory documentation for importers.

Manufacturer / TM Owner

Santen Oy

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Levofloxacin, a fluoroquinolone antibiotic, is used to treat bacterial infections affecting several organ systems.

  • Community‑acquired pneumonia: reduces bacterial load and improves respiratory symptoms.
  • Acute bacterial sinusitis: eradicates causative pathogens, relieving sinus congestion.
  • Uncomplicated urinary tract infection: eliminates uropathogens, alleviating dysuria and frequency.

How It Works

  • Levofloxacin inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV, enzymes essential for DNA replication, transcription, and repair. By stabilizing the enzyme–DNA complex, it prevents the resealing of DNA strands, leading to bacterial cell death. This bactericidal action is broad‑spectrum against Gram‑negative and Gram‑positive organisms.

Side Effects

Levofloxacin may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Nausea: mild to moderate stomach upset.
  • Diarrhea: loose stools, sometimes watery.
  • Headache: transient cranial discomfort.
  • Dizziness: sensation of light‑headedness.
  • Abdominal pain: cramping or discomfort.
  • Insomnia: difficulty falling or staying asleep.

Serious or Rare Side Effects

  • Tendon rupture: sudden tendon pain or rupture, especially in the Achilles.
  • QT interval prolongation: risk of cardiac arrhythmias.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Clostridioides difficile infection: severe colitis with watery diarrhea.
  • Peripheral neuropathy: tingling or numbness in extremities.
  • Stevens‑Johnson syndrome: severe skin blistering and mucosal involvement.

Precautions & Warnings

Before prescribing Levofloxacin, clinicians should consider several safety factors.

  • Assess renal function: dose adjustment may be required in renal impairment.
  • Avoid in patients with known hypersensitivity to fluoroquinolones.
  • Use with caution in elderly: higher risk of tendon injury and CNS effects.
  • Do not co‑administer with antacids containing aluminum or magnesium without appropriate spacing.
  • Monitor QT interval in patients with cardiac risk factors.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Levofloxacin can interact with other medicines, altering efficacy or safety.

Major Interactions (Avoid)

  • Concurrent use with other fluoroquinolones: increased risk of toxicity.
  • Co‑administration with systemic corticosteroids: heightened tendon rupture risk.
  • Combination with drugs that prolong QT interval (e.g., macrolides, antiarrhythmics): risk of cardiac arrhythmia.

Moderate Interactions (Monitor Closely)

  • Antacids or supplements containing calcium, iron, zinc, or magnesium: reduce levofloxacin absorption; separate dosing by at least 2 hours.
  • Warfarin: may enhance anticoagulant effect; monitor INR closely.
  • Theophylline: increased plasma levels; observe for signs of toxicity.

Frequently Asked Questions

Oftaquix contains levofloxacin, a fluoroquinolone antibiotic that is prescribed to treat a variety of bacterial infections, including community‑acquired pneumonia, acute bacterial sinusitis, and uncomplicated urinary tract infections. It works against both Gram‑negative and Gram‑positive organisms when used under medical supervision.

Levofloxacin inhibits bacterial DNA gyrase and topoisomerase IV, enzymes required for DNA replication and transcription. By blocking these enzymes, it prevents bacterial DNA from unwinding and resealing, leading to bacterial cell death and resolution of the infection.

The appropriate dose of Oftaquix is determined by the prescribing clinician based on the type and severity of the infection, patient age, weight, renal function, and local treatment guidelines. Dosage regimens are not standardized in public information and must be individualized.

Levofloxacin is generally classified as a pregnancy category C medication, meaning risk cannot be ruled out. It is usually avoided unless the potential benefit justifies the risk. Breastfeeding mothers should consult a healthcare professional, as the drug can be excreted in milk and may affect the infant.

To order Oftaquix, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Oftaquix (levofloxacin) offers a broad spectrum of activity and a once‑daily dosing option for many infections, which can improve adherence compared with some older fluoroquinolones that require multiple daily doses. Its pharmacokinetic profile provides high tissue penetration, but safety considerations such as tendon risk and QT prolongation are similar across the class.

Oftaquix tablets should be stored at room temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and avoid storing in humid or excessively hot environments.

Oftaquix is supplied as oral tablets that are taken with a full glass of water. The tablets should be swallowed whole and not crushed or chewed unless specifically instructed by a healthcare professional. Dosing intervals and duration are set by the prescriber.

Serious risks include tendon rupture (especially in the Achilles tendon), QT interval prolongation leading to potentially fatal arrhythmias, severe allergic reactions such as anaphylaxis, Clostridioides difficile‑associated colitis, peripheral neuropathy, and rare but life‑threatening skin reactions like Stevens‑Johnson syndrome.

Oftaquix should be avoided in individuals with a known hypersensitivity to levofloxacin or any fluoroquinolone, patients with a history of tendon disorders related to fluoroquinolone use, those with a prolonged QT interval not corrected, and patients receiving concomitant therapy that significantly increases the risk of tendon injury or cardiac arrhythmias.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.