Product image of Okidol (Ketoprofen Lysine) supplied by GNH India

Okidol

Active Ingredient:
Ketoprofen Lysine
Origin:
EU

Okidol (Ketoprofen Lysine)

Ketoprofen lysine, the active ingredient in Okidol, is a non-steroidal anti-inflammatory drug (NSAID) presented as a 50 mg tablet for oral use. It is employed to relieve pain and inflammation in musculoskeletal conditions and is commonly prescribed for adults.

GNH India supplies Okidol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dompé Farmaceutici S.P.A.

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Indications & Clinical Uses

Okidol is an NSAID that acts on inflammatory pathways to reduce pain and swelling.

  • Rheumatoid arthritis: helps decrease joint pain and swelling, improving mobility.
  • Osteoarthritis: provides analgesic relief for chronic joint degeneration.
  • Acute musculoskeletal injury: alleviates pain and inflammation following sprains, strains or bruises.

How It Works

  • Ketoprofen lysine inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, reducing the synthesis of prostaglandins that mediate inflammation, pain and fever. This blockade diminishes peripheral sensitisation of nociceptors and limits the inflammatory response at the site of tissue injury.

Side Effects

Ketoprofen lysine may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Dyspepsia or stomach upset
  • Headache
  • Dizziness
  • Nausea
  • Mild skin rash
  • Elevated liver enzymes

Serious or Rare Side Effects

  • Gastrointestinal bleeding or ulceration
  • Severe skin reactions such as Stevens‑Johnson syndrome
  • Renal impairment or failure
  • Hepatotoxicity
  • Anaphylaxis or severe allergic reaction
  • Cardiovascular events such as myocardial infarction

Precautions & Warnings

When using Okidol, consider the following safety measures:

  • Assess renal function: patients with impaired kidney function require monitoring.
  • Evaluate hepatic status: liver disease may increase risk of toxicity.
  • Review cardiovascular risk: NSAIDs can affect blood pressure and clotting.
  • Avoid concurrent use with other NSAIDs or anticoagulants unless medically justified.
  • Use gastro‑protective agents if long‑term therapy is anticipated.
  • Store at ambient temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Ketoproline lysine can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin) – increased bleeding risk.
  • Selective COX‑2 inhibitors (e.g., celecoxib) – additive gastrointestinal toxicity.\nModerate Interactions (Monitor Closely):
  • ACE inhibitors or ARBs – may reduce renal perfusion.
  • Diuretics – heightened risk of kidney injury.
  • Lithium – NSAIDs can raise lithium serum levels.
  • Methotrexate – reduced clearance may increase toxicity.

Frequently Asked Questions

Okidol contains ketoprofen lysine, an NSAID indicated for the relief of pain and inflammation associated with rheumatoid arthritis, osteoarthritis and acute musculoskeletal injuries such as sprains or strains. It is prescribed to improve mobility and reduce discomfort in these conditions.

Ketoprofen lysine works by inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which are required for prostaglandin synthesis. Lower prostaglandin levels decrease inflammation, pain signalling and fever, providing symptomatic relief at the site of injury or disease.

The appropriate dose of Okidol is determined by the prescribing clinician based on the patient’s condition, age, weight and renal‑hepatic function. The prescriber will set the strength, frequency and duration of therapy according to clinical guidelines.

Ketoprofen lysine, like other NSAIDs, is generally avoided in the third trimester of pregnancy because of potential fetal cardiovascular effects. It should only be used during pregnancy or lactation if the benefit outweighs the risk and after consultation with a healthcare professional.

To order Okidol, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Okidol (ketoprofen lysine) offers a rapid onset of analgesia compared with some NSAIDs due to its lysine salt form, which improves gastrointestinal absorption. Its efficacy is comparable to ibuprofen or naproxen, while its safety profile aligns with class‑wide NSAID risks such as gastrointestinal and renal effects.

Okidol tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and heat. Keep the container tightly closed and out of direct sunlight.

Okidol is supplied as oral tablets that are swallowed whole with a full glass of water. It may be taken with or without food, although taking it with meals can reduce the likelihood of stomach upset.

Serious risks include gastrointestinal bleeding or ulceration, severe skin reactions such as Stevens‑Johnson syndrome, renal impairment, hepatotoxicity and increased cardiovascular events. Patients should be monitored for signs of bleeding, rash, changes in urine output or chest pain.

Okidol is contraindicated in individuals with known hypersensitivity to ketopro‑or any NSAID, active gastrointestinal ulcer disease, severe heart failure, advanced renal or liver failure, and in late‑term pregnancy. It should also be avoided in patients taking other NSAIDs unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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