Product image of Okitask (Ketoprofen Lysine) supplied by GNH India

Okitask

Active Ingredient:
Ketoprofen Lysine
Origin:
EU

Okitask (Ketoprofen Lysine)

Ketoprofen lysine, the active ingredient in Okitask, is a non‑steroidal anti‑inflammatory drug presented as a tablet for oral use. It is employed to relieve pain and inflammation associated with musculoskeletal disorders, rheumatoid arthritis and other inflammatory conditions in adults.

GNH India supplies Okitask as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dompé Farmaceutici S.P.A.

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Indications & Clinical Uses

Ketoprofen lysine is an NSAID that reduces inflammation and pain in several musculoskeletal and inflammatory conditions.

  • Rheumatoid arthritis: helps reduce joint pain, swelling and stiffness.
  • Osteoarthritis: alleviates pain and improves joint function.
  • Acute musculoskeletal injury: provides short‑term relief of pain and inflammation.
  • Post‑operative pain: used as part of multimodal analgesia after surgery.
  • Dysmenorrhea: reduces menstrual‑related pelvic pain.

How It Works

  • Ketoprofen lysine inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing the synthesis of prostaglandins that mediate inflammation, pain and fever. By limiting prostaglandin production at sites of tissue injury, it reduces vascular permeability, edema and nociceptor activation, providing anti‑inflammatory and analgesic effects.

Side Effects

Ketoprofen lysine may cause a range of adverse reactions, most of which are dose‑dependent and reversible.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or light‑headedness.
  • Skin rash or mild itching.
  • Elevated liver enzymes.

Serious or Rare Side Effects

  • Peptic ulcer disease or gastrointestinal bleeding.
  • Severe skin reactions such as Stevens‑Johnson syndrome.
  • Renal impairment or acute kidney injury.
  • Hepatotoxicity with marked liver enzyme elevation.
  • Anaphylactic or severe allergic reactions.

Precautions & Warnings

When prescribing ketoprofen lysine, clinicians should evaluate patient history and monitor for potential complications.

  • Cardiovascular risk: avoid in patients with uncontrolled hypertension or recent thrombotic events.
  • Gastrointestinal safety: use with caution in those with a history of ulcers or bleeding.
  • Renal function: assess baseline kidney function and adjust use in chronic kidney disease.
  • Hepatic health: monitor liver enzymes in patients with liver disease.
  • Concomitant NSAIDs or anticoagulants: increase risk of bleeding.
  • Store at ambient temperature: keep below 25°C, in original packaging, protected from moisture.

Avoid Interactions

Ketoprofen lysine can interact with several drug classes, altering efficacy or safety.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): heightened risk of serious bleeding.
  • Selective COX‑2 inhibitors (e.g., celecoxib): additive gastrointestinal toxicity.
  • High‑dose aspirin (high > 325 mg/day).

Moderate Interactions (Monitor Closely)

  • ACE inhibitors (e.g., enalapril): may reduce antihypertensive effect.
  • Diuretics (e.g., furosemide): potential for reduced renal perfusion.
  • Lithium: increased serum lithium levels.
  • Methotrexate: decreased renal clearance, raising toxicity risk.

Frequently Asked Questions

Okitask contains ketoprofen lysine, an NSAID indicated for the relief of pain and inflammation associated with conditions such as rheumatoid arthritis, osteoarthritis, acute musculoskeletal injuries, post‑operative pain and dysmenorrhea. It is prescribed for adult patients who need anti‑inflammatory and analgesic therapy.

Ketoprofen lysine works by inhibiting the cyclo‑oxygenase enzymes COX‑1 and COX‑2, which reduces the formation of prostaglandins—key mediators of inflammation, pain and fever. Lower prostaglandin levels decrease vascular permeability, edema and nociceptor activation, providing anti‑inflammatory and analgesic effects.

The specific dose of Okitask is determined by the prescribing clinician based on the patient’s condition, severity of symptoms, age, renal and hepatic function, and concomitant medications. Healthcare professionals tailor the regimen to achieve optimal pain control while minimizing risk.

Ketoprofen lysine, like other NSAIDs, is generally avoided during the third trimester of pregnancy because it may affect fetal cardiovascular function. Use during early pregnancy or while breastfeeding should only be considered if the potential benefit outweighs the risk, and after consultation with a qualified healthcare provider.

To request Okitask, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Okitask (ketoprofen lysine) offers potent anti‑inflammatory and analgesic activity comparable to other NSAIDs such as ibuprofen or diclofenac, but its lysine salt formulation may provide faster absorption and onset of action. Choice of NSAID depends on individual patient risk factors, tolerability, and specific clinical scenarios.

Okitask tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keeping the product in a dry, cool place helps maintain its stability and potency throughout its shelf life.

Okitask is supplied as oral tablets and is taken by mouth with a full glass of water. It can be taken with or without food, although taking it with food may reduce gastrointestinal discomfort. Patients should follow the dosing instructions provided by their prescriber.

Serious risks include gastrointestinal bleeding or ulceration, severe skin reactions such as Stevens‑Johnson syndrome, renal impairment, hepatotoxicity, and anaphylactic reactions. Patients should be monitored for signs of bleeding, rash, changes in urine output, or liver dysfunction, and seek immediate medical attention if these occur.

Okitask is contraindicated in patients with known hypersensitivity to ketoprofen or other NSAIDs, those with active gastrointestinal ulceration or bleeding, severe heart failure, and in the third trimester of pregnancy. Caution is also advised for individuals with significant renal or hepatic impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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