Product image of Olanzapină Teva (Olanzapine) supplied by GNH India

Olanzapină Teva

Active Ingredient:
Olanzapine
Origin:
EU

Olanzapină Teva (Olanzapine)

Olanzapine, the active ingredient in Olanzapină Teva, is an atypical antipsychotic presented as an oral formulation for buccal, oral, and sublingual use. It is prescribed for the treatment of schizophrenia and bipolar I disorder in adult patients, helping to control psychotic symptoms and mood instability.

GNH India supplies Olanzapină Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to stringent quality standards and providing reliable global distribution with comprehensive regulatory support.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

  • Olanzapine is used in the management of psychiatric disorders that involve dopamine and serotonin dysregulation.
  • Schizophrenia: reduces psychotic symptoms and lowers relapse risk.
  • Bipolar I disorder (manic episodes): stabilizes mood and decreases manic symptoms.
  • Maintenance therapy: helps prevent recurrence of psychotic or mood episodes.

How It Works

  • Olanzapine acts as an antagonist at dopamine D2 and serotonin 5‑HT2A receptors, while also interacting with other neurotransmitter receptors such as histamine H1, muscarinic, and adrenergic sites. This combined receptor blockade modulates dopaminergic and serotonergic pathways, leading to reduced psychotic and manic symptoms in affected patients.

Side Effects

Common Side Effects

  • Weight gain: increased body mass and appetite.
  • Sedation: drowsiness or fatigue.
  • Dry mouth: reduced salivation.
  • Constipation: decreased bowel movements.

Serious or Rare Side Effects

  • Neuroleptic malignant syndrome: life‑threatening reaction with fever and muscle rigidity.
  • Agranulocytosis: severe drop in white blood cells.
  • Severe hyperglycemia: marked increase in blood glucose levels.
  • Tardive dyskinesia: involuntary, repetitive movements.
  • Myocarditis: inflammation of the heart muscle.

Precautions & Warnings

  • Olanzapină Teva requires careful monitoring and adherence to safety guidelines.
  • Monitor metabolic parameters: regularly assess weight, glucose, and lipid levels.
  • Observe for extrapyramidal symptoms: watch for movement disorders or rigidity.
  • Evaluate cardiac status: perform ECG if risk factors for QT prolongation exist.
  • Review hepatic function: adjust use in patients with liver impairment.
  • Store at ambient temperature: keep below 25°C, protect from moisture and light.

Avoid Interactions

Olanzapină Teva may interact with several concomitant medications.

Major Interactions (Avoid)

  • Concomitant antipsychotics: increased risk of CNS depression.
  • Strong CYP1A2 inhibitors (e.g., fluvoxamine): may raise olanzapine plasma levels.
  • CNS depressants (e.g., benzodiazepines, opioids): additive sedation.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., carbamazepine): may lower olanzapine concentrations.
  • Antihypertensives: potential enhancement of orthostatic hypotension.
  • Anticholinergic agents: may increase anticholinergic burden.

Frequently Asked Questions

Olanzapină Teva is a generic formulation of olanzapine indicated for the treatment of schizophrenia and bipolar I disorder in adults. It helps control psychotic symptoms, such as hallucinations and delusions, and stabilizes mood swings associated with manic episodes.

Olanzapine works by blocking dopamine D2 and serotonin 5‑HT2A receptors, among other neurotransmitter sites. This antagonism reduces dopaminergic and serotonergic activity that underlies psychotic and manic symptoms, leading to improved mental state and mood regulation.

The prescribed dose of Olanzapină Teva is individualized by a qualified healthcare professional. The prescriber determines the appropriate amount based on the patient’s specific condition, clinical response, and tolerability, following the dosing guidelines in the official prescribing information.

Safety of Olanzapină Teva during pregnancy and lactation has not been fully established. It should only be used when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by the treating physician.

To order Olanzapină Teva, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any required import documentation.

Compared with typical antipsychotics, olanzapine has a lower incidence of extrapyramidal side effects but a higher propensity for metabolic changes such as weight gain and glucose elevation. It is often preferred for its efficacy in both schizophrenia and bipolar disorder, offering a broader therapeutic profile.

Olanzapină Teva should be stored at ambient temperature below 25 °C, in its original packaging, protected from moisture and light. Keep the product out of reach of children and do not store in a location where temperature may exceed the recommended range.

The medication is taken orally, either swallowed whole or dissolved for buccal or sublingual administration as directed by the prescriber. It may be taken with or without food according to the label instructions, and the dosing schedule should be followed precisely.

Serious risks include neuroleptic malignant syndrome, severe hyperglycemia, agranulocytosis, and tardive dyskinesia. Patients should be monitored for fever, muscle rigidity, sudden changes in blood sugar, signs of infection, or involuntary movements, and seek immediate medical attention if any occur.

Olanzapină Teva should not be used by individuals with known hypersensitivity to olanzapine or any excipients in the formulation, as well as patients with uncontrolled narrow‑angle glaucoma or severe hepatic impairment, unless a physician determines that the benefits outweigh the risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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