Product image of Olanzapine Viatris (Olanzapine) supplied by GNH India

Olanzapine Viatris

Active Ingredient:
Olanzapine
Origin:
EU

Olanzapine Viatris (Olanzapine)

Olanzapine, the active ingredient in Olanzapine Viatris, is an antipsychotic presented as an oral tablet for oral use. It is indicated for the management of schizophrenia and bipolar I disorder in adult patients. The medication works by modulating neurotransmitter activity in the brain, helping to reduce psychotic symptoms and stabilize mood.

GNH India supplies Olanzapine Viatris as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable logistics for global distribution, ensuring consistent product availability and regulatory compliance.

Manufacturer / TM Owner

Viatris Limited

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Indications & Clinical Uses

Olanzapine is an atypical antipsychotic that acts on dopamine and serotonin pathways to treat serious mental health conditions.

  • Schizophrenia: reduces hallucinations, delusions and thought disorder.
  • Bipolar I disorder (manic episodes): helps control mood swings and mania.
  • Schizoaffective disorder: alleviates combined psychotic and mood symptoms.

How It Works

  • Olanzapine exerts its therapeutic effect primarily by antagonizing dopamine D2 and serotonin 5‑HT2A/2C receptors, while also exhibiting affinity for histamine H1, muscarinic, and alpha‑1 adrenergic receptors. This broad receptor profile modulates neurotransmission, leading to reduced psychotic symptoms and mood stabilization.

Side Effects

Olanzapine may cause a range of adverse reactions, varying from mild to severe.

Common Side Effects

  • Weight gain
  • Sedation
  • Dry mouth
  • Constipation

Serious or Rare Side Effects

  • Neuroleptic malignant syndrome
  • Tardive dyskinesia
  • Severe hyperglycemia
  • Leukopenia

Precautions & Warnings

When prescribing Olanzapine, clinicians should consider several safety measures.

  • Monitor metabolic parameters: regularly check weight, fasting glucose and lipid profile.
  • Assess for extrapyramidal symptoms: observe for tremor, rigidity or abnormal movements.
  • Evaluate cardiovascular effects: monitor blood pressure and heart rate.
  • Use caution in hepatic impairment: dose adjustment may be required.
  • Avoid abrupt discontinuation: taper under medical supervision.
  • Store at ambient temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Olanzapine can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • CNS depressants (alcohol, benzodiazepines) may increase sedation.
  • CYP1A2 inhibitors (e.g., fluvoxamine, ciprofloxacin) can raise olanzapine plasma levels.
  • QT‑prolonging agents (certain antiarrhythmics) may increase cardiac risk.

Moderate Interactions (Monitor Closely)

  • CYP2D6 substrates (metoprolol) may have altered clearance.
  • Smoking induces CYP1A2, potentially lowering olanzapine exposure.
  • Antidiabetic agents may need dose adjustment due to olanzapine‑induced hyperglycemia.

Frequently Asked Questions

Olanzapine Viatris is an oral antipsychotic medication indicated for the treatment of schizophrenia and for the management of manic or mixed episodes associated with bipolar I disorder in adult patients.

Olanzapine works by blocking dopamine D2 receptors and serotonin 5‑HT2A/2C receptors in the brain, while also affecting histamine, muscarinic and adrenergic receptors. This broad receptor antagonism helps to reduce psychotic symptoms and stabilize mood.

The appropriate dose of Olanzapine is individualized and determined by the prescribing healthcare professional based on the patient’s condition, response to therapy and tolerability. No fixed dosing regimen is provided here.

Olanzapine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus. It is excreted in breast milk, so breastfeeding is generally not recommended unless the infant’s benefit outweighs the possible risks.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Olanzapine is classified as an atypical antipsychotic and is often noted for its efficacy in treating both positive and negative symptoms of schizophrenia, as well as mood stabilization in bipolar disorder. Compared with some other atypicals, it may have a higher propensity for metabolic side effects such as weight gain and glucose elevation.

Olanzapine tablets should be stored at ambient temperature, below 25 °C, in the original packaging to protect them from moisture and light. Keep the product out of reach of children and do not use after the expiry date.

Olanzapine Viatris is taken orally, usually once daily, with or without food, as directed by the prescribing clinician. The tablets should be swallowed whole with a glass of water and not chewed or crushed unless specifically instructed.

Serious risks include neuroleptic malignant syndrome, tardive dyskinesia, severe hyperglycemia or new‑onset diabetes, and leukopenia or agranulocytosis. Patients should seek immediate medical attention if they experience high fever, muscle rigidity, sudden changes in mood, unexplained infections or abnormal blood counts.

Olanzapine is contraindicated in individuals with known hypersensitivity to olanzapine or any of its excipients. Caution is advised for patients with uncontrolled diabetes, severe cardiovascular disease, hepatic impairment, or a history of neuroleptic malignant syndrome.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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