Product image of Oleovit D3 (Colecalciferol) supplied by GNH India

Oleovit D3

Active Ingredient:
Colecalciferol
Origin:
EU

Oleovit D3 (Colecalciferol)

Colecalciferol, the active ingredient in Oleovit D3, is a Vitamin D presented as an oral supplement for oral use. It is used to correct vitamin D deficiency and support bone health in individuals with insufficient sunlight exposure or dietary intake.

GNH India supplies Oleovit D3 as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing and regulatory support across multiple markets, and our distribution network ensures timely delivery and compliance with local import requirements.

Manufacturer / TM Owner

Fresenius Kabi Austria Gmbh

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Indications & Clinical Uses

Oleovit D3 (colecalciferol) is used to address disorders related to vitamin D deficiency and bone metabolism.

  • Vitamin D deficiency: restores normal serum 25‑hydroxyvitamin D concentrations.
  • Osteomalacia: improves bone mineralization and reduces bone pain.
  • Rickets in children: supports proper bone growth and prevents skeletal deformities.

How It Works

  • Colecalciferol is converted in the liver to 25‑hydroxyvitamin D and subsequently in the kidney to the active hormone 1,25‑dihydroxyvitamin D. This active form binds to vitamin D receptors in intestinal cells, enhancing transcription of calcium‑binding proteins and increasing absorption of calcium and phosphate, which promotes bone mineralization and maintains serum calcium homeostasis.

Side Effects

Oleovit D3 may cause adverse reactions, which are categorized by frequency.

Common Side Effects

  • Hypercalcemia: mild elevation of blood calcium levels.
  • Nausea: occasional stomach upset.
  • Constipation: reduced bowel movements.
  • Headache: transient head discomfort.
  • Dry mouth: sensation of oral dryness.
  • Fatigue: feeling of tiredness.

Serious or Rare Side Effects

  • Severe hypercalcemia: marked elevation of calcium causing cardiac arrhythmia.
  • Renal stones: formation of calcium‑based kidney stones.
  • Allergic reactions: rash, itching, or swelling, potentially progressing to anaphylaxis.
  • Hypercalciuria: excessive urinary calcium excretion leading to kidney damage.

Precautions & Warnings

Before initiating Oleovit D3, certain precautions should be observed to ensure safe use.

  • Baseline assessment: check serum calcium and 25‑hydroxyvitamin D levels.
  • Monitoring: repeat vitamin D and calcium tests periodically during therapy.
  • Renal impairment: adjust dose or avoid if severe kidney disease is present.
  • Hypercalcemia: discontinue if significant hypercalcemia develops.
  • Pregnancy and lactation: use only if clearly needed and prescribed.
  • Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Oleovit D3 can interact with other medicines, altering its effectiveness or safety.

Major Interactions (Avoid)

  • Thiazide diuretics: increase risk of hypercalcemia.
  • High‑dose calcium supplements: may cause excessive calcium levels.
  • Vitamin A excess: potentiates hypercalcemia.

Moderate Interactions (Monitor Closely)

  • Anticonvulsants (e.g., phenytoin, phenobarbital): accelerate vitamin D metabolism, reducing efficacy.
  • Glucocorticoids: increase vitamin D catabolism, possibly requiring higher doses.
  • Orlistat: decreases intestinal absorption of fat‑soluble vitamins, including vitamin D.

Frequently Asked Questions

Oleovit D3 contains colecalciferol, a form of vitamin D, and is used to correct vitamin D deficiency, support normal bone mineralization, and manage conditions such as osteomalacia and rickets when prescribed by a healthcare professional.

Colecalciferol is first converted in the liver to 25‑hydroxyvitamin D and then in the kidney to the active hormone 1,25‑dihydroxyvitamin D. This active form binds to vitamin D receptors, increasing intestinal absorption of calcium and phosphate, which are essential for bone health and calcium balance.

The appropriate dose of Oleovit D3 is determined by the prescribing clinician based on the patient’s serum vitamin D level, age, weight, and clinical condition. Dosage may vary widely, and patients should follow the specific instructions provided by their healthcare provider.

Oleovit D3 may be used during pregnancy or lactation only if the prescriber deems it necessary. Vitamin D is important for fetal bone development, but the decision should be individualized, and the lowest effective dose should be selected to avoid excess calcium.

To order Oleovit D3, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs) and assists with import documentation.

Oleovit D3 provides colecalciferol, the same active ingredient found in many vitamin D supplements. Compared with ergocalciferol (vitamin D2), colecalciferol generally has a longer half‑life and may achieve more stable serum levels, making it a preferred choice for many clinicians.

Oleovit D3 should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and discard any product that appears discolored or compromised.

Oleovit D3 is taken orally, usually with water. It can be taken with or without food, but consistent administration with respect to meals helps maintain stable absorption. Patients should follow the dosing schedule prescribed by their healthcare professional.

The most serious risks include severe hypercalcemia, which can cause cardiac arrhythmias, renal stones, and kidney damage. Rarely, allergic reactions such as rash, swelling, or anaphylaxis may occur. Patients should seek immediate medical attention if they experience symptoms of high calcium or an allergic response.

Oleovit D3 should be avoided in individuals with known hypersensitivity to colecalciferol or any excipients, those with untreated hypercalcemia, and patients with severe renal impairment unless specifically directed by a physician. Pregnant or nursing women should only use it under medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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