Product image of Oleunor Peri-N4e (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin) supplied by GNH India

Oleunor Peri-N4e

Active Ingredient:
Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin
Origin:
EU

Oleunor Peri-N4e (Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serin)

Valine, Alanine, Arginine, Histidine, Isoleucine, Leucine, Methionine, Phenylalanine, Proline, Serine, the active ingredient in Oleunor Peri-N4e, is a nutrition supplement presented as a solution for intravenous use. It supports protein synthesis and metabolic needs in patients requiring parenteral nutrition.
GNH India supplies Oleunor Peri-N4e as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, transplant centres, oncology centres, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Noridem Enterprises Ltd

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Indications & Clinical Uses

Oleunor Peri-N4e is used as an intravenous amino‑acid formulation to address nutritional deficits in several clinical settings.

  • Parenteral nutrition: provides essential and non‑essential amino acids for patients unable to take oral nutrition.
  • Post‑operative recovery: supports tissue repair and protein synthesis after major surgery.
  • Critical illness: helps maintain nitrogen balance and metabolic stability in intensive‑care patients.

How It Works

  • The amino‑acid blend supplies the building blocks required for protein synthesis, stimulates mTOR signaling pathways, and contributes to nitrogen balance. By delivering essential and conditionally essential amino acids directly into the bloodstream, the formulation bypasses gastrointestinal absorption, facilitating rapid utilization for tissue repair, immune function, and metabolic homeostasis.

Side Effects

Intravenous administration of Oleunor Peri-N4e may be associated with several adverse reactions.

Common Side Effects

  • Infusion site irritation: redness or discomfort at the injection site.
  • Mild nausea: transient feeling of queasiness during or after infusion.
  • Headache: occasional mild to moderate headache.
  • Transient hyperglycemia: temporary rise in blood glucose levels.

Serious or Rare Side Effects

  • Anaphylactic reaction: severe allergic response requiring immediate medical attention.
  • Electrolyte imbalance: disturbances in potassium, sodium, or calcium levels.
  • Metabolic acidosis: rare but serious shift in blood pH.
  • Severe hypotension: sudden drop in blood pressure during infusion.

Precautions & Warnings

Prior to initiating therapy with Oleunor Peri-N4e, clinicians should consider several safety measures.

  • Assess renal function: adjust dosing in patients with impaired kidney function.
  • Monitor blood glucose: amino‑acid solutions can affect glucose metabolism.
  • Check for allergies: avoid use in individuals with known hypersensitivity to any component.
  • Avoid concurrent high‑dose electrolytes: may increase risk of electrolyte overload.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Oleunor Peri-N4e may interact with other medications or therapies.

Major Interactions (Avoid)

  • High‑dose insulin therapy: increased risk of severe hypoglycemia.
  • Co‑administration with other parenteral nutrition solutions: potential electrolyte and volume overload.

Moderate Interactions (Monitor Closely)

  • Loop diuretics: monitor electrolytes and fluid balance.
  • Renal replacement therapy: adjust amino‑acid load as needed.
  • Corticosteroids: may increase protein catabolism, requiring closer nutritional assessment.
  • Anticonvulsants: possible alteration of amino‑acid metabolism.

Frequently Asked Questions

Oleunor Peri-N4e is an intravenous amino‑acid formulation used to provide essential and non‑essential amino acids to patients who cannot receive adequate nutrition orally. It is commonly employed in parenteral nutrition, post‑operative recovery, and critical‑care settings to support protein synthesis, tissue repair, and metabolic stability.

The blend supplies the body’s building blocks for protein synthesis and activates cellular pathways such as mTOR that regulate growth and repair. Delivered directly into the bloodstream, the amino acids bypass the digestive tract, allowing rapid utilization for muscle maintenance, immune function, and overall nitrogen balance.

The prescribed dose of Oleunor Peri-N4e is determined by the treating physician based on the patient’s weight, clinical condition, renal function, and nutritional requirements. Dosing regimens are individualized and should follow the prescriber’s specific instructions.

Safety data for Oleunor Peri-N4e in pregnancy or lactation are limited. It should only be used if the potential benefit justifies any potential risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To order Oleunor Peri-N4e, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details (including cold‑chain if needed), and import documentation.

Oleunor Peri-N4e offers a comprehensive amino‑acid profile that includes both essential and non‑essential amino acids, providing balanced nutrition similar to other high‑quality parenteral formulations. Compared with products that contain only essential amino acids, it may better support overall protein synthesis and metabolic needs in critically ill patients.

Oleunor Peri-N4e should be stored at 2‑8 °C, protected from light, and kept in its original container. Do not freeze or shake the solution. Before administration, inspect for particulate matter and ensure the solution is at room temperature if required by the infusion protocol.

Oleunor Peri-N4e is administered intravenously, typically as an infusion added to a compatible carrier fluid. The rate and duration of infusion are set by the prescribing clinician and should be monitored for tolerance and any adverse reactions.

The most serious risks include anaphylactic reactions, severe electrolyte disturbances, metabolic acidosis, and significant hypotension during infusion. Prompt recognition and management of these events are essential, and patients should be monitored closely throughout administration.

Oleunor Peri-N4e should be avoided in individuals with known hypersensitivity to any of its amino‑acid components or the infusion vehicle. Caution is also advised for patients with severe renal or hepatic impairment, uncontrolled electrolyte disorders, or those at high risk for anaphylaxis.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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