Olfen (Diclofenac Diethylamine)

Diclofenac diethylamine is an NSAID that reduces inflammation and pain in the musculoskeletal system.

• Osteoarthritis: Reduces joint pain and improves mobility.
• Rheumatoid arthritis: Alleviates joint inflammation and stiffness.
• Acute musculoskeletal injuries: Provides short‑term pain relief for sprains, strains and bruises.

• Diclofenac diethylamine inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes in peripheral tissues, decreasing the synthesis of prostaglandins that mediate inflammation, pain and fever. The topical formulation allows the drug to penetrate the skin and act locally at the site of inflammation while limiting systemic exposure.

Adverse reactions to topical diclofenac are generally mild and localized, but systemic effects can occur.

Common Side Effects

• Skin irritation: Redness, itching or burning at the application site.
• Pruritus: Itchy skin around the treated area.
• Dryness: Localized skin dryness.
• Erythema: Mild redness of the skin.
• Contact dermatitis: Allergic skin reaction.

Serious or Rare Side Effects

• Systemic hypersensitivity: Rash, hives, or angio‑edema.
• Gastrointestinal bleeding: Ulceration or bleeding in the stomach or intestines.
• Liver injury: Elevated liver enzymes or hepatitis.
• Renal impairment: Decreased kidney function or fluid retention.
• Cardiovascular events: Increased risk of heart attack or stroke.

When using Olfen, consider the following safety measures:

• Contraindication: Do not use if you or the patient has a known allergy to diclofenac or other NSAIDs.
• Pregnancy: Avoid the if any w  
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