Product image of Olfen (Diclofenac Sodium) supplied by GNH India

Olfen

Active Ingredient:
Diclofenac Sodium
Origin:
EU

Olfen (Diclofenac Sodium)

Diclofenac Sodium, the active ingredient in Olfen, is a nonsteroidal anti-inflammatory drug presented as a pharmaceutical preparation for buccal, cutaneous, dental and intradermal use. It reduces inflammation and pain in a range of musculoskeletal and dental conditions for adult patients.
GNH India supplies Olfen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Pharmaceuticals Cr, S.R.O.

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Indications & Clinical Uses

Diclofenac Sodium is an NSAID that acts on inflammatory pathways to relieve pain and swelling.

  • Pain relief: Provides analgesic effect in acute and chronic pain conditions.
  • Inflammation reduction: Decreases swelling and redness in inflamed tissues.
  • Musculoskeletal disorders: Alleviates symptoms of osteoarthritis, rheumatoid arthritis and soft‑tissue injuries.
  • Dental pain: Controls postoperative and dental procedure‑related discomfort.

How It Works

  • Diclofenac Sodium inhibits cyclooxygenase (COX‑1 and COX‑2) enzymes, which blocks the conversion of arachidonic acid to prostaglandins. By lowering prostaglandin synthesis, it reduces the inflammatory response, pain signaling, and fever generation at the site of tissue injury.

Side Effects

Adverse reactions may occur with diclofenac use and are categorized by frequency.

Common Side Effects

  • Gastrointestinal discomfort: nausea, dyspepsia or abdominal pain.
  • Headache: mild to moderate intensity.
  • Dizziness or vertigo.
  • Skin rash or pruritus.

Serious or Rare Side Effects

  • Hepatic toxicity: elevated liver enzymes or hepatitis.
  • Renal impairment: reduced kidney function or acute kidney injury.
  • Severe allergic reactions: anaphylaxis, Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Gastrointestinal ulceration or bleeding, and increased cardiovascular risk.

Precautions & Warnings

Before initiating therapy, consider patient‑specific factors and safety measures.

  • Assess renal function: use caution in patients with impaired kidney function.
  • Evaluate hepatic status: avoid in severe liver disease.
  • Review cardiovascular risk: limit use in patients with known heart disease or stroke history.
  • Avoid concurrent NSAIDs or anticoagulants unless medically justified.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Diclofenac may interact with several drug classes, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or corticosteroids: heightened gastrointestinal toxicity.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors or diuretics: possible reduction in renal function.
  • Lithium: increased serum lithium levels.
  • Methotrexate: reduced clearance leading to toxicity.

Frequently Asked Questions

Olfen contains diclofenac sodium, an NSAID that is commonly prescribed to manage pain, reduce inflammation, and treat musculoskeletal disorders such as osteoarthritis and rheumatoid arthritis, as well as dental pain following procedures.

Diclofenac sodium works by inhibiting the cyclooxygenase enzymes COX‑1 and COX‑2, which are essential for prostaglandin production. Lower prostaglandin levels lead to decreased inflammation, pain signaling, and fever at the site of injury.

The appropriate dose of Olfen is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and renal or hepatic function. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Diclofenac sodium is generally not recommended during pregnancy, especially in the third trimester, due to potential risks to the fetus. Breastfeeding mothers should consult their physician, as diclofenac can be excreted in breast milk and may affect the infant.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Olfen’s active ingredient, diclofenac sodium, offers potent anti‑inflammatory and analgesic effects comparable to ibuprofen or naproxen, but it may have a higher risk of gastrointestinal and cardiovascular side effects. Choice of NSAID depends on the patient’s risk profile and therapeutic needs.

Olfen should be stored at room temperature, ideally below 25 °C. Keep the product in its original packaging, protect it from moisture and direct sunlight, and ensure the container is tightly closed to maintain stability.

Olfen can be applied buccally, cutaneously, or used in dental settings as directed by a healthcare professional. The route of administration depends on the formulation and the specific clinical indication for which it is prescribed.

Serious risks include gastrointestinal bleeding or ulceration, severe allergic reactions such as anaphylaxis or Stevens‑Johnson syndrome, liver toxicity, kidney impairment, and an increased risk of cardiovascular events like heart attack or stroke.

Olfen should be avoided in patients with known hypersensitivity to diclofenac or other NSAIDs, those with active gastrointestinal ulcers, severe heart failure, uncontrolled hypertension, or significant renal or hepatic impairment unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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