Product image of Olfen (Diclofenac Sodium, Lidocaine Hydrochloride) supplied by GNH India

Olfen

Active Ingredient:
Diclofenac Sodium, Lidocaine Hydrochloride
Origin:
EU

Olfen (Diclofenac Sodium, Lidocaine Hydrochloride)

Diclofenac sodium, the active ingredient in Olfen, is a non‑steroidal anti‑inflammatory drug (NSAID) presented as a topical formulation for local pain relief use. It reduces inflammation and provides analgesia, often combined with a local anesthetic to enhance comfort in musculoskeletal conditions.

GNH India supplies Olfen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva B.V

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Indications & Clinical Uses

Olfen combines diclofenac sodium and lidocaine hydrochloride to address pain and inflammation in several musculoskeletal and dermatologic contexts. It is commonly employed for:

  • Osteoarthritis: reduces joint pain and improves mobility.
  • Rheumatoid arthritis: alleviates inflammatory joint discomfort.
  • Acute musculoskeletal sprains and strains: provides rapid local pain relief.
  • Post‑operative wound pain: minimizes discomfort after minor surgical procedures.
  • Tendinitis and bursitis: eases inflammation and associated pain.

How It Works

  • Diclofenac sodium inhibits cyclo‑oxygenase (COX‑1 and COX‑2) enzymes, decreasing prostaglandin synthesis that mediates inflammation and pain. Lidocaine hydrochloride stabilises neuronal membranes by blocking voltage‑gated sodium channels, producing a local anaesthetic effect that further reduces pain signals at the application site.

Side Effects

Adverse reactions to Olfen may vary in frequency and severity.

Common Side Effects

  • Skin irritation at the application site: redness or itching.
  • Gastrointestinal discomfort: mild nausea or dyspepsia.
  • Headache: transient mild headache.
  • Dizziness: occasional light‑headed feeling.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Cardiovascular events: chest pain or signs of heart attack.
  • Liver enzyme elevation: abnormal liver function tests.
  • Blood disorders: unexplained bruising or bleeding.

Precautions & Warnings

When using Olfen, consider the following safety measures:

  • Assess cardiovascular risk: patients with heart disease may need monitoring.
  • Evaluate renal function: adjust use in patients with impaired kidney function.
  • Monitor gastrointestinal health: avoid in individuals with active ulcers.
  • Review concomitant NSAID use: limit combined NSAID exposure to reduce toxicity.
  • Pregnancy and lactation: avoid unless clearly indicated by a physician.
  • Store at below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Olfen may interact with several medication classes; awareness helps prevent adverse events.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased bleeding risk.
  • Other NSAIDs or COX‑2 inhibitors: heightened gastrointestinal toxicity.
  • Corticosteroids: additive risk of ulceration and bleeding.

Moderate Interactions (Monitor Closely)

  • ACE inhibitors (e.g., enalapril): possible reduction in renal function.
  • Diuretics (e.g., furosemide): may enhance renal effects of NSAIDs.
  • Selective serotonin reuptake inhibitors (SSRIs): increased bleeding tendency.

Frequently Asked Questions

Olfen is a topical formulation that combines diclofenac sodium, an NSAID, with lidocaine hydrochloride, a local anesthetic. It is used to relieve pain and reduce inflammation associated with musculoskeletal conditions such as osteoarthritis, rheumatoid arthritis, sprains, strains, tendinitis and post‑operative wound discomfort.

Diclofenac sodium blocks cyclo‑oxygenase enzymes (COX‑1 and COX‑2), which lowers prostaglandin production. Reduced prostaglandins lead to decreased inflammation and pain at the site of application.

The prescribed dose of Olfen is determined by the treating clinician based on the patient’s condition, severity of pain and the specific product strength. Patients should follow the healthcare professional’s instructions and the product label.

Olfen should only be used during pregnancy or lactation if a physician determines that the benefit outweighs potential risks. Generally, NSAIDs and topical anesthetics are avoided, especially in the third trimester, unless specifically advised by a healthcare provider.

To order Olfen, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Olfen combines an NSAID (diclofenac) with a local anesthetic (lidocaine), offering both anti‑inflammatory and analgesic effects. Compared with single‑ingredient topical NSAIDs, Olfen may provide faster pain relief due to the added lidocaine, though individual response varies and safety profiles should be considered.

Olfen should be stored at temperatures below 25 °C, in its original packaging, protected from moisture and direct sunlight. Maintaining these conditions helps preserve the stability and efficacy of both diclofenac and lidocaine.

Olfen is applied topically to the affected skin area, typically in a thin layer, and gently massaged until absorbed. The exact frequency and amount should follow the prescribing clinician’s directions and the product’s labeling.

Serious risks include severe allergic reactions such as rash, swelling or breathing difficulty, cardiovascular events like chest pain, liver enzyme elevations, and blood‑related disorders such as unexplained bruising or bleeding. Patients should seek immediate medical attention if any of these occur.

Olfen is contraindicated in individuals with known hypersensitivity to diclofenac, lidocaine or any formulation components, as well as patients with active gastrointestinal ulcers, severe heart failure, significant renal or hepatic impairment, and in late‑stage pregnancy unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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